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Gene Expression Data
Assay Details
Assay
Reference: J:332639 Rinta-Jaskari MM, et al., Temporally and Spatially Regulated Collagen XVIII Isoforms Are Involved in Ureteric Tree Development Via the TSP1-like Domain. Matrix Biol. 2023 Jan 6;
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7735109
Gene symbol: Col18a1
Gene name: collagen, type XVIII, alpha 1
Results
Specimen 3a WT: embryonic day 12.5 (more )
Note: Double labeled: green - Col18a1; red - Krt8 (assay MGI:7735110).
Structure Level Pattern Image Note
TS20: ureteric tip Present Regionally restricted 3a WT Expression throughout basement membrane of ureteric tips.
TS20: primitive collecting duct Present Widespread 3a WT Expression throughout the ureteric tree.
Specimen 3a -/-: embryonic day 12.5; Col18a1tm1Hms/Col18a1tm1Hms (more )
Note: Double labeled: green - Col18a1; red - Krt8 (assay MGI:7735110).
Structure Level Pattern Image Note
TS20: metanephros Absent 3a Col18a1-/- Expression absent in kidney.
Specimen 3a P1/P1: embryonic day 12.5; Col18a1tm1Pih/Col18a1tm1Pih (more )
Note: Double labeled: green - Col18a1; red - Krt8 (assay MGI:7735110).
Structure Level Pattern Image Note
TS20: ureteric trunk Present Regionally restricted 3a Col18a1 P1/P1 Expression only in stalk area of forming ureteric tree.
TS20: ureteric tip Absent 3a Col18a1 P1/P1
Specimen 3a P2/P2: embryonic day 12.5; Col18a1tm2Pih/Col18a1tm2Pih (more )
Note: Double labeled: green - Col18a1; red - Krt8 (assay MGI:7735110).
Structure Level Pattern Image Note
TS20: ureteric tip Present Regionally restricted 3a Col18a1 P2/P2 Expression throughout basement membrane of ureteric tips, likely reflecting short form.
Specimen 3b WT: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: ureteric tip Present Regionally restricted 3b WT Expression throughout basement membrane of ureteric tips.
TS22: ureteric trunk Present Regionally restricted 3b WT Expression in basement membrane of stalk of ureteric tree.
Specimen 3b -/-: embryonic day 14.5; Col18a1tm1Hms/Col18a1tm1Hms (more )
Structure Level Pattern Image Note
TS22: metanephros Absent 3b Col18a1-/- Expression absent in kidney.
Specimen 3b P1/P1: embryonic day 14.5; Col18a1tm1Pih/Col18a1tm1Pih (more )
Structure Level Pattern Image Note
TS22: ureteric trunk Present Regionally restricted 3b Col18a1 P1/P1 Expression only in stalk area of forming ureteric tree.
TS22: ureteric tip Absent 3b Col18a1 P1/P1
Specimen 3b P2/P2: embryonic day 14.5; Col18a1tm2Pih/Col18a1tm2Pih (more )
Structure Level Pattern Image Note
TS22: ureteric tip Present Regionally restricted 3b Col18a1 P2/P2 Expression throughout basement membrane of ureteric tips, likely reflecting short form.
Specimen 3c WT: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: ureteric tip Present Regionally restricted 3c WT Expression throughout basement membrane of ureteric tips.
TS22: ureteric trunk Present Regionally restricted 3c WT Expression in basement membrane of stalk of ureteric tree.
Specimen 3c -/-: embryonic day 14.5; Col18a1tm1Hms/Col18a1tm1Hms (more )
Structure Level Pattern Image Note
TS22: metanephros Absent 3c Col18a1-/- Expression absent in kidney.
Specimen 3c P1/P1: embryonic day 14.5; Col18a1tm1Pih/Col18a1tm1Pih (more )
Structure Level Pattern Image Note
TS22: ureteric trunk Present Regionally restricted 3C Col18a1 P1/P1 Expression only in stalk area of forming ureteric tree.
TS22: ureteric tip Absent 3C Col18a1 P1/P1
Specimen 3c P2/P2: embryonic day 14.5; Col18a1tm2Pih/Col18a1tm2Pih (more )
Structure Level Pattern Image Note
TS22: ureteric tip Present Regionally restricted 3c Col18a1 P2/P2 Expression throughout basement membrane of ureteric tips, likely reflecting short form.
Specimen 7b: embryonic day 16.5 (more )
Note: Double labeled: red - Col18a1; green - Krt8 (assay MGI:7735110).
Structure Level Pattern Image Note
TS24: collecting duct Present Regionally restricted 7b Expression in branching tubules.
Specimen 7d: embryonic day 16.5; Col18a1tm1Hms/Col18a1tm1Hms (more )
Note: Double labeled: red - Col18a1; green - Krt8 (assay MGI:7735110).
Structure Level Pattern Image Note
TS24: collecting duct Absent 7d
Specimen 7f: embryonic day 16.5 (more )
Note: Double labeled: green - Col18a1; red - Itgb1 (assay MGI:7735116).
Structure Level Pattern Image Note
TS24: collecting duct Present Regionally restricted 7f Expression in branching tubules.
Specimen 7g: embryonic day 16.5; Col18a1tm1Hms/Col18a1tm1Hms (more )
Note: Double labeled: green - Col18a1; red - Itgb1 (assay MGI:7735116).
Structure Level Pattern Image Note
TS24: collecting duct Absent 7g
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory