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Gene Expression Data
Assay Details
Assay
Reference: J:353283 Yermalovich AV, et al., An essential role for Cmtr2 in mammalian embryonic development. Dev Biol. 2024 Jul 31;516:47-58
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7734885
Gene symbol: Ly76
Gene name: lymphocyte antigen 76
Antibody: clone TER-119
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2B Remodeled WT: embryonic day 9.5 (more )
Structure Cell Type Level Pattern Image Note
TS15: yolk sac blood cell Present 2B Remodeled plexus Terr-119 , 2B Remodeled plexus Merged
TS15: yolk sac blood vessel blood cell Present 2B Remodeled plexus Terr-119 , 2B Remodeled plexus Merged
Specimen 2B Full plexus: embryonic day 9.5; Cmtr2tm1.1(KOMP)Vlcg/Cmtr2tm1.1(KOMP)Vlcg (more )
Structure Cell Type Level Pattern Image Note
TS15: yolk sac blood cell Present Regionally restricted 2B Full plexus Terr-119 , 2B Full plexus Merged In some mutant blood cells are distributed from the blood islands into more-proximal regions of the plexus.
Specimen 2B Partial plexus: embryonic day 9.5; Cmtr2tm1.1(KOMP)Vlcg/Cmtr2tm1.1(KOMP)Vlcg (more )
Structure Cell Type Level Pattern Image Note
TS15: yolk sac blood cell Present 2B Partial plexus Terr-119 , 2B Partial plexus Merged In some mutant blood cells are distributed from the blood islands into more-proximal regions of the plexus.
Specimen 3B Control: embryonic day 10.5; Cmtr2em1Smoc/Cmtr2+ (more )
Structure Cell Type Level Pattern Image Note
TS17: yolk sac blood cell Present 3B Merged Control , 3B Terr-119 Control
TS17: yolk sac blood vessel blood cell Present 3B Merged Control , 3B Terr-119 Control
Specimen 3B Remodeled plexus: embryonic day 10.5; Cmtr2em1Smoc/Cmtr2em1Smoc, Tg(Tek-cre)12Flv/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS17: yolk sac blood cell Present 3B Remodeled plexus Terr-119 , 3B Remodeled plexus Merged Staining indicates that this mutant has impairments in vascular remodeling compared to littermate controls.
Specimen 3B Partly Remodeled: embryonic day 10.5; Cmtr2em1Smoc/Cmtr2em1Smoc, Tg(Tek-cre)12Flv/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS17: yolk sac blood cell Present 3B Partly remodeled Terr-119 , 3B Partly remodeled Merged Staining indicates that this mutant has impairments in vascular remodeling compared to littermate controls.
Specimen 3B Full plexus: embryonic day 10.5; Cmtr2em1Smoc/Cmtr2em1Smoc, Tg(Tek-cre)12Flv/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS17: yolk sac blood cell Present 3B Full plexus Terr-119 , 3B Full plexus Merged Staining indicates that this mutant has impairments in vascular remodeling compared to littermate controls.
Specimen S2A +/+: embryonic day 10.5 (more )
Structure Cell Type Level Pattern Image Note
TS17: yolk sac blood cell Present S2A Remodeled plexus Terr-119 , S2A Remodeled plexus Merged
Specimen S2A -/-: embryonic day 10.5; Cmtr2tm1.1(KOMP)Vlcg/Cmtr2tm1.1(KOMP)Vlcg (more )
Structure Cell Type Level Pattern Image Note
TS17: yolk sac blood cell Present S2A Full plexus Merged , S2A Full plexus Terr-119 In some mutant blood cells are distributed from the blood islands into more-proximal regions of the plexus.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory