Axin2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:279388 Weiss AC, et al., Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme. J Pathol. 2019 Aug;248(4):452-463
Assay type:	RNA in situ
MGI Accession ID:	MGI:7718896
Gene symbol:	Axin2
Gene name:	axin 2

Probe:	Axin2 probe
Probe preparation:	Antisense labelled with digoxigenin RNA

Results

Specimen S9 control: embryonic day 14.5; Gata2^tm1Sac/? (more

)
Note: Littermates without the Tbx18^cre were used as control.

Structure	Level	Pattern	Image	Note
TS22: ureteral mesenchyme	Present	Regionally restricted	S9_control Axin2	Expression was detected in the inner ureteric mesenchyme.

Specimen S9 Gata2cKO: embryonic day 14.5; Gata2^tm1Sac/Gata2^tm1Sac, Tbx18^tm4(cre)Akis/Tbx18⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS22: ureteral mesenchyme	Present	Regionally restricted	S9_Gata2cKO Axin2	Expression in the Gata2cKO inner ureteric mesenchyme was unchanged.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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