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Gene Expression Data
Assay Details
Assay
Reference: J:279388 Weiss AC, et al., Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme. J Pathol. 2019 Aug;248(4):452-463
Assay type: RNA in situ
MGI Accession ID: MGI:7718849
Gene symbol: Tnnt2
Gene name: troponin T2, cardiac
Probe: Tnnt2 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2Q: embryonic day 18.5; Gata2tm1Sac/? (more )
Note: Littermates without the Tbx18cre were used as control.
Structure Cell Type Level Pattern Image Note
TS26: ureteral smooth muscle layer ureter smooth muscle cell Present 2Q
Specimen 2R: embryonic day 18.5; Gata2tm1Sac/Gata2tm1Sac, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: ureteral smooth muscle layer ureter smooth muscle cell Trace 2R Expression was severely reduced in the Gata2cKO.
Specimen 3C E14.5 control: embryonic day 14.5; Gata2tm1Sac/? (more )
Note: Littermates without the Tbx18cre were used as control.
Structure Level Pattern Image Note
TS22: ureteral mesenchyme Ambiguous 3C control E14.5 Tnnt2
Specimen 3C E14.5 Gata2cKO: embryonic day 14.5; Gata2tm1Sac/Gata2tm1Sac, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: ureteral mesenchyme Absent 3C Gata2cKO E14.5 Tnnt2
Specimen 3C E15.5 control: embryonic day 15.5; Gata2tm1Sac/? (more )
Note: Littermates without the Tbx18cre were used as control.
Structure Cell Type Level Pattern Image Note
TS23: ureteral smooth muscle layer ureter smooth muscle cell Present 3C control E15.5 Tnnt2
Specimen 3C E15.5 Gata2cKO: embryonic day 15.5; Gata2tm1Sac/Gata2tm1Sac, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS23: ureteral smooth muscle layer ureter smooth muscle cell Absent 3C Gata2cKO E15.5 Tnnt2
Specimen 3C E16.5 control: embryonic day 16.5; Gata2tm1Sac/? (more )
Note: Littermates without the Tbx18cre were used as control.
Structure Cell Type Level Pattern Image Note
TS24: ureteral smooth muscle layer ureter smooth muscle cell Present 3C control E16.5 Tnnt2
Specimen 3C E16.5 Gata2cKO: embryonic day 16.5; Gata2tm1Sac/Gata2tm1Sac, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS24: ureteral smooth muscle layer ureter smooth muscle cell Absent 3C Gata2cKO E16.5 Tnnt2
Specimen S4Q: embryonic day 18.5; Gata2tm1Sac/? (more )
Note: Littermates without the Tbx18cre were used as control.
Structure Cell Type Level Pattern Image Note
TS26: ureteral smooth muscle layer ureter smooth muscle cell Present S4Q
Specimen S4R: embryonic day 18.5; Gata2tm1Sac/Gata2tm1Sac, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: ureteral smooth muscle layer ureter smooth muscle cell Trace S4R Expression was severely reduced in the Gata2cKO.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory