Gene Expression Data
Assay Details
Assay
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Reference:
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J:69975
Cai J, et al., Mice lacking the Nkx6.2 (Gtx) homeodomain transcription factor develop and reproduce normally. Mol Cell Biol. 2001 Jul;21(13):4399-403
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7712219
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Gene symbol:
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Mbp
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Gene name:
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myelin basic protein
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Probe:
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MBP probe
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Probe preparation:
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labelled with digoxigenin RNA
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Results
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Specimen
5A:
embryonic day 18.5
(more )
Specimen
5A:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: spinal cord |
Present |
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5A
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Expression detected as early as E18.5
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Specimen
5B:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Nkx6-2tm1Qiu/Nkx6-2tm1Qiu
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Age:
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embryonic day 18.5
|
Sex:
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Not Specified
|
Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: spinal cord |
Present |
|
5B
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No significant difference in onset or intensity of expression compared to wild type.
|
Specimen
5C:
postnatal adult
(more )
Specimen
5C:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: spinal cord |
Present |
|
5C
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Expression persists in adults.
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Specimen
5D:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
|
Nkx6-2tm1Qiu/Nkx6-2tm1Qiu
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: spinal cord |
Present |
|
5D
|
No significant difference in onset or intensity of expression compared to wild type.
|
Specimen
6A:
postnatal adult
(more )
Specimen
6A:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
6B:
(close )
Genetic Background:
|
Not Specified
|
Mutant Allele(s):
|
Nkx6-2tm1Qiu/Nkx6-2tm1Qiu
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: corpus callosum |
Present |
|
6B
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Expression similar to that of wild type.
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Specimen
6C:
postnatal adult
(more )
Specimen
6C:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
6D:
(close )
Genetic Background:
|
Not Specified
|
Mutant Allele(s):
|
Nkx6-2tm1Qiu/Nkx6-2tm1Qiu
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
|