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Gene Expression Data
Assay Details
Assay
Reference: J:166892 Cariboni A, et al., Defective gonadotropin-releasing hormone neuron migration in mice lacking SEMA3A signalling through NRP1 and NRP2: implications for the aetiology of hypogonadotropic hypogonadism. Hum Mol Genet. 2011 Jan 15;20(2):336-44
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7708022
Gene symbol: Prph
Gene name: peripherin
Antibody: Anti-peripherin
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1A: embryonic day 14.5 (more )
Note: Double labeled: green - Prph; red - Nrp2 (assay MGI:7708023).
Structure Level Pattern Image Note
TS22: vomeronasal branch of olfactory I nerve Present Regionally restricted 1A' , 1A Expression was detected in vomeronasal axons in the nasal compartment. Colocalization with Nrp2 was observed.

Specimen 1B: embryonic day 14.5 (more )
Note: Double labeled: green - Prph; red - Nrp1 (assay MGI:7708024).
Structure Level Pattern Image Note
TS22: vomeronasal branch of olfactory I nerve Present Regionally restricted 1B , 1B' Expression was detected in vomeronasal axons in the nasal compartment. Colocalization with Nrp1 was observed.

Specimen 4B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: vomeronasal branch of olfactory I nerve Present Regionally restricted 4B Expression was detected in vomeronasal axons in the nasal compartment/olfactory bulb and the basal forebrain.

Specimen 4D: embryonic day 14.5; Sema3atm1.1Tyag/Sema3atm1.1Tyag (more )
Structure Level Pattern Image Note
TS22: vomeronasal branch of olfactory I nerve Present Regionally restricted 4D Mistargeted axons were observed between the olfactory bulbs.

Specimen 4F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forebrain Present Regionally restricted 4F Expression was detected in vomeronasal axons in the basal forebrain.
TS22: vomeronasal branch of olfactory I nerve Present Regionally restricted 4F Expression was detected in vomeronasal axons in the basal forebrain.

Specimen 4H: embryonic day 14.5; Sema3atm1.1Tyag/Sema3atm1.1Tyag (more )
Structure Level Pattern Image Note
TS22: forebrain Absent 4H The vomeronasal axons were lacking in the basal forebrain of the mutant.

Specimen 6C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: vomeronasal branch of olfactory I nerve Present Regionally restricted 6C , 6D Wild-type contained peripherin-positive axons in the nose that were projecting normally through the cribriform plate and olfactory bulb.

Specimen 6H: embryonic day 14.5; Nrp1tm1Ddg/Nrp1tm1Ddg, Nrp2tm1Ddg/Nrp2tm1Ddg (more )
Structure Level Pattern Image Note
TS22: vomeronasal branch of olfactory I nerve Present Regionally restricted 6H , 6I Mutants contained ectopic immunolabeled axons in the area between the olfactory bulbs.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory