Otp RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:171421 Vandunk C, et al., Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus. J Neurosci. 2011 Apr 27;31(17):6457-67
Assay type:	RNA in situ
MGI Accession ID:	MGI:7660848
Gene symbol:	Otp
Gene name:	orthopedia homeobox

Probe:	MTF#191
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

1_Otp ©

Specimen 1: postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: suprachiasmatic nucleus	Absent		1_Otp
TS27: diencephalon	Present	Regionally restricted	1_Otp	Expression was detected at the lateral and dorsal boundaries, but not within the suprachiasmatic nucleus.

8B top Otp ©

Specimen 8B Six3^flox/flox;Nestin-cre^-: embryonic day 18.5-19.5; Six3^tm2Gco/Six3^tm2Gco (more

)

Structure	Level	Pattern	Image	Note
TS26: zona incerta	Present		8B top Otp

Specimen 8B Six3^flox/flox;Nestin-cre⁺: embryonic day 18.5-19.5; Six3^tm2Gco/Six3^tm2Gco, Tg(Nes-cre)1Kln/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: zona incerta	Present		8B bottom Otp	The mutant mice retained expression.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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