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Gene Expression Data
Assay Details
Assay
Reference: J:154534 Martinez G, et al., Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation. Invest Ophthalmol Vis Sci. 2009 Oct;50(10):4794-806
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7659207
Gene symbol: Maf
Gene name: MAF bZIP transcription factor
Antibody: Anti-c-Maf
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5E: embryonic day 13.5 (more )
Note: Fixation was either 10% neutral buffered formalin or 4% paraformaldehyde. Embedding was either in paraffin or OCT (cryosection).
Structure Level Pattern Image Note
TS21: lens Present Regionally restricted 5E Intense nuclear immunoreactivity was detected as cells leave the germinative zone and cross the equator.
Specimen 5F: embryonic day 13.5; Ctnnb1tm1Mmt/Ctnnb1tm1Mmt, Tg(Cryaa-cre,Tyr)39Mlr/0 (more )
Note: Conditional mutant. Fixation was either 10% neutral buffered formalin or 4% paraformaldehyde. Embedding was either in paraffin or OCT (cryosection).
Structure Level Pattern Image Note
TS21: lens Present Regionally restricted 5F Intense nuclear immunoreactivity was detected as cells leave the germinative zone and cross the equator.
Specimen 5G: embryonic day 13.5; Ctnnb1tm1Mmt/Ctnnb1tm1Mmt, Tg(Cryaa-cre)10Mlr/0 (more )
Note: Conditional mutant. Fixation was either 10% neutral buffered formalin or 4% paraformaldehyde. Embedding was either in paraffin or OCT (cryosection).
Structure Level Pattern Image Note
TS21: lens Weak Regionally restricted 5G Immunoreactivity was decreased and delayed in the mutant.
Specimen 5H: embryonic day 13.5; Apctm1Tno/Apctm1Tno, Tg(Cryaa-cre)10Mlr/0 (more )
Note: Conditional mutant. Fixation was either 10% neutral buffered formalin or 4% paraformaldehyde. Embedding was either in paraffin or OCT (cryosection).
Structure Level Pattern Image Note
TS21: lens Weak Regionally restricted 5H Immunoreactivity was decreased and delayed in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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