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Gene Expression Data
Assay Details
Assay
Reference: J:347747 Plummer NW, et al., A knock-in allele of Hand2 expressing Dre recombinase. Genesis. 2024;62(3):e23601
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7645546
Gene symbol: Hand2
Gene name: heart and neural crest derivatives expressed 2
Reporter: Dre
Probe: Mm-Dre-Cust (442641)
Probe preparation: Antisense
Visualized with: Chromogenic
Assay notes: RNAscope assay.
Results
Specimen 2b: embryonic day 10.5; Hand2em1(dre)Pjen/Hand2+ (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component Present 2b
TS17: bulbus cordis Present 2b
TS17: heart atrium Present 2b
TS17: hindlimb bud Present 2b
TS17: sympathetic nerve trunk Present 2b Expression is seen in the sympathetic chain.
TS17: brain Absent 2b

Specimen 2d: embryonic day 14.5; Hand2em1(dre)Pjen/Hand2+ (more )
Structure Level Pattern Image Note
TS22: heart Present 2d
TS22: mandible Present 2d
TS22: superior cervical ganglion Present 2d
TS22: tongue Present 2d

Specimen 2f: embryonic day 14.5; Hand2em1(dre)Pjen/Hand2+ (more )
Structure Level Pattern Image Note
TS22: heart ventricle Present 2f
TS22: sympathetic ganglion Present 2f

Specimen 2h: embryonic day 14.5; Hand2em1(dre)Pjen/Hand2+ (more )
Structure Level Pattern Image Note
TS22: hindlimb cartilage condensation Present 2h
TS22: enteric nervous system Present 2h Expression is seen in enteric neurons lining the gut.

Specimen 2j: embryonic day 14.5; Hand2em1(dre)Pjen/Hand2+ (more )
Structure Level Pattern Image Note
TS22: enteric nervous system Present 2j Expression is seen in enteric neurons lining the gut.

Specimen 2l: embryonic day 14.5; Hand2em1(dre)Pjen/Hand2+ (more )
Structure Level Pattern Image Note
TS22: adrenal gland Present 2l


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory