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Gene Expression Data
Assay Details
Assay
Reference: J:347747 Plummer NW, et al., A knock-in allele of Hand2 expressing Dre recombinase. Genesis. 2024;62(3):e23601
Assay type: RNA in situ
MGI Accession ID: MGI:7645545
Gene symbol: Hand2
Gene name: heart and neural crest derivatives expressed 2
Probe: Mm-Hand2 (499821)
Probe preparation: Antisense
Visualized with: Chromogenic
Assay notes: RNAscope assay.
Results
Specimen 2a: embryonic day 10.5; Hand2em1(dre)Pjen/Hand2+ (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component Present 2a
TS17: bulbus cordis Present 2a
TS17: heart atrium Present 2a
TS17: hindlimb bud Present 2a
TS17: sympathetic nerve trunk Present 2a Expression is seen in the sympathetic chain.
TS17: brain Absent 2a

Specimen 2c: embryonic day 14.5; Hand2em1(dre)Pjen/Hand2+ (more )
Structure Level Pattern Image Note
TS22: heart Present 2c
TS22: mandible Present 2c
TS22: superior cervical ganglion Present 2c
TS22: tongue Present 2c

Specimen 2e: embryonic day 14.5; Hand2em1(dre)Pjen/Hand2+ (more )
Structure Level Pattern Image Note
TS22: heart ventricle Present 2e
TS22: sympathetic ganglion Present 2e

Specimen 2g: embryonic day 14.5; Hand2em1(dre)Pjen/Hand2+ (more )
Structure Level Pattern Image Note
TS22: hindlimb cartilage condensation Present 2g
TS22: enteric nervous system Present 2g Expression is seen in enteric neurons lining the gut.

Specimen 2i: embryonic day 14.5; Hand2em1(dre)Pjen/Hand2+ (more )
Structure Level Pattern Image Note
TS22: enteric nervous system Present 2i Expression is seen in enteric neurons lining the gut.

Specimen 2k: embryonic day 14.5; Hand2em1(dre)Pjen/Hand2+ (more )
Structure Level Pattern Image Note
TS22: adrenal gland Present 2k


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory