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Gene Expression Data
Assay Details
Assay
Reference: J:308858 Fu M, et al., 37/67-laminin receptor facilitates neural crest cell migration during enteric nervous system development. FASEB J. 2020 Aug;34(8):10931-10947
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7639768
Gene symbol: Elavl3
Gene name: ELAV like RNA binding protein 3
Antibody: Anti-HuC/D
Detection system: Secondary antibody coupled to Cy3
Assay notes: The specificity of the antibody used was not detailed; both family members have been annotated.
Results
Specimen 1A NCC+/+: postnatal day 7-11; Ednrbtm1Nrd/Ednrbtm1Nrd (more )
Note: Colonic myenteric plexus. Double labeled: red - Elavl3 and Elavl4; green - Rpsa (assay MGI:7639815).
Structure Cell Type Level Pattern Image Note
TS28: myenteric nerve plexus enteric neuron Present 1A +/+ merge , 1A +/+ HuC/D
Specimen 1A NCC-/-: postnatal day 7-11; Ednrbtm1Nrd/Ednrbtm1Nrd, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Colonic myenteric plexus. Double labeled: red - Elavl3 and Elavl4; green - Rpsa (assay MGI:7639815).
Structure Cell Type Level Pattern Image Note
TS28: myenteric nerve plexus enteric neuron Present 1A -/- merge , 1A -/- HuC/D
Specimen 1B NCC+/+: postnatal day 7-11; Ednrbtm1Nrd/Ednrbtm1Nrd (more )
Note: Colonic myenteric plexus. Double labeled: red - Elavl3 and Elavl4; green - Rpsa (assay MGI:7639814).
Structure Cell Type Level Pattern Image Note
TS28: myenteric nerve plexus enteric neuron Present 1B +/+ merge , 1B +/+ HuC/D
Specimen 1B NCC-/-: postnatal day 7-11; Ednrbtm1Nrd/Ednrbtm1Nrd, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Colonic myenteric plexus. Double labeled: red - Elavl3 and Elavl4; green - Rpsa (assay MGI:7639814).
Structure Cell Type Level Pattern Image Note
TS28: myenteric nerve plexus enteric neuron Present 1B -/- HuC/D , 1B -/- merge
Specimen S2 NCC+/+: postnatal; Ednrbtm1Nrd/Ednrbtm1Nrd (more )
Note: Small intestine myenteric plexus. Double labeled: red - Elavl3 and Elavl4; green - Rpsa (assay MGI:7639814).
Structure Cell Type Level Pattern Image Note
TS28: myenteric nerve plexus enteric neuron Present S2+/+ HuC/D , S2+/+ merge
Specimen S2 NCC-/-: postnatal; Ednrbtm1Nrd/Ednrbtm1Nrd, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Small intestine myenteric plexus. Double labeled: red - Elavl3 and Elavl4; green - Rpsa (assay MGI:7639814).
Structure Cell Type Level Pattern Image Note
TS28: myenteric nerve plexus enteric neuron Present S2-/- merge , S2-/- HuC/D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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