About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:347585 Leon NY, et al., Y chromosome damage underlies testicular abnormalities in ATR-X syndrome. iScience. 2024 May 17;27(5):109629
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7628673
Gene symbol: Daxx
Gene name: Fas death domain-associated protein
Antibody: Anti-Daxx (M-112; sc-7152)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1C Control: embryonic day 16.5; Atrxtm1Rjg/Y (more )
Note: Double labeled: green - Daxx; red - Gata4 (assay MGI:7628670).
Structure Cell Type Level Pattern Image Note
TS24: Sertoli cell Sertoli cell Present Regionally restricted 1C Control (merged) , 1C Control DAXX Expression co-localized with Gata4 expression in control Sertoli cells.
Specimen 1C ScAttrxKO: embryonic day 16.5; Atrxtm1Rjg/Y, Plekha5Tg(AMH-cre)1Flor/0 (more )
Note: Conditional mutant. Double labeled: green - Daxx; red - Gata4 (assay MGI:7628670).
Structure Cell Type Level Pattern Image Note
TS24: Sertoli cell Sertoli cell Absent 1C ScAtrxKO (merged) , 1C ScAtrxKO DAXX Expression absent in mutant Sertoli cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory