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Gene Expression Data
Assay Details
Assay
Reference: J:335878 Montanes-Agudo P, et al., The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes. Cardiovasc Res. 2023 May 22;119(5):1161-1174
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7618956
Gene symbol: Qki
Gene name: quaking, KH domain containing RNA binding
Results
Specimen 1E cQKI WT: embryonic day 14.5; Tg(Myh6-cre)2182Mds/0 (more )
Note: Double labeled: green - Qki; red - Tnni2 (assay MGI:7618957).
Structure Cell Type Level Pattern Image Note
TS22: heart cardiac muscle cell Present 1E cQKI WT Expression in cardiomyocytes of 4 chambers of heart.
Specimen 1E cQKI KO: embryonic day 14.5; Qkitm1.1Rchd/Qkitm1.1Rchd, Tg(Myh6-cre)2182Mds/0 (more )
Note: Conditional mutant. Double labeled: green - Qki; red - Tnni2 (assay MGI:7618957).
Structure Level Pattern Image Note
TS22: heart Trace Regionally restricted 1E cQKI KO Residual expression particularly in cells of compact myocardium and middle axis of heart.
Specimen 1F cQKI WT: embryonic day 12.5; Tg(Myh6-cre)2182Mds/0 (more )
Note: Double labeled: green - Qki; red - Tnni2 (assay MGI:7618957).
Structure Cell Type Level Pattern Image Note
TS20: heart left ventricle cardiac muscle cell Present 1F cQKI WT panQKI , 1F cQKI WT Merged
Specimen 1F cQKI KO: embryonic day 12.5; Qkitm1.1Rchd/Qkitm1.1Rchd, Tg(Myh6-cre)2182Mds/0 (more )
Note: Conditional mutant. Double labeled: green - Qki; red - Tnni2 (assay MGI:7618957).
Structure Level Pattern Image Note
TS20: heart left ventricle Weak 1F cQKI KO pan QKI , 1F cQKI KO Merged Expresssion clearly reduced compared to control.
Specimen S2 cQKI WT E10.5: embryonic day 10.5; Tg(Myh6-cre)2182Mds/0 (more )
Note: Double labeled: green - Qki; red - Tnni2 (assay MGI:7618957).
Structure Cell Type Level Pattern Image Note
TS17: heart cardiac muscle cell Present S2_cQKI WT E10.5 panQKI , S2_cQKI WT E10.5 Overlay Expression in cardiomyocytes of 4 chambers of heart.
Specimen S2 cQKI KO E10.5: embryonic day 10.5; Qkitm1.1Rchd/Qkitm1.1Rchd, Tg(Myh6-cre)2182Mds/0 (more )
Note: Conditional mutant. Double labeled: green - Qki; red - Tnni2 (assay MGI:7618957).
Structure Level Pattern Image Note
TS17: heart Weak S2_cQKI KO E10.5 panQKI , S2_cQKI KO E10.5 Overlay Expresssion clearly reduced compared to control.
Specimen S2 cQKI WT E12.5: embryonic day 12.5; Tg(Myh6-cre)2182Mds/0 (more )
Note: Double labeled: green - Qki; red - Tnni2 (assay MGI:7618957).
Structure Cell Type Level Pattern Image Note
TS20: heart cardiac muscle cell Present S2_cQKI WT E12.5 panQKI , S2_cQKI WT E12.5 Overlay Expression in cardiomyocytes of 4 chambers of heart.
Specimen S2 cQKI KO E12.5: embryonic day 12.5; Qkitm1.1Rchd/Qkitm1.1Rchd, Tg(Myh6-cre)2182Mds/0 (more )
Note: Conditional mutant. Double labeled: green - Qki; red - Tnni2 (assay MGI:7618957).
Structure Level Pattern Image Note
TS20: heart Weak S2_cQKI KO E12.5 Overlay , S2_cQKI KO E12.5 panQKI Expresssion clearly reduced compared to control.
Specimen S2 cQKI WT E14.5: embryonic day 14.5; Tg(Myh6-cre)2182Mds/0 (more )
Note: Double labeled: green - Qki; red - Tnni2 (assay MGI:7618957).
Structure Cell Type Level Pattern Image Note
TS22: heart cardiac muscle cell Present S2_cQKI WT E14.5 Overlay , S2_cQKI WT E14.5 panQKI Expression in cardiomyocytes of 4 chambers of heart.
Specimen S2 cQKI KO E14.5: embryonic day 14.5; Qkitm1.1Rchd/Qkitm1.1Rchd, Tg(Myh6-cre)2182Mds/0 (more )
Note: Conditional mutant. Double labeled: green - Qki; red - Tnni2 (assay MGI:7618957).
Structure Level Pattern Image Note
TS22: heart Trace S2_cQKI KO E14.5 Overlay , S2_cQKI KO E14.5 panQKI Residual expression particularly in cells of compact myocardium and middle axis of heart.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
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