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Gene Expression Data
Assay Details
Assay
Reference: J:345775 Gomez-Ospina N, et al., A promoter in the coding region of the calcium channel gene CACNA1C generates the transcription factor CCAT. PLoS One. 2013;8(4):e60526
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7616360
Gene symbol: Cacna1c
Gene name: calcium channel, voltage-dependent, L type, alpha 1C subunit
Antibody: anti-CCAT
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S4E Brain: embryonic day 11.5; Cacna1ctm1.2Red/Cacna1c+ (more )
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted S4E Brain CCAT , S4E Brain Merged Cytoplasmic and membranous expression in developing neural tissue.
Specimen S4E Heart: embryonic day 11.5; Cacna1ctm1.2Red/Cacna1c+ (more )
Structure Level Pattern Image Note
TS19: cardiac muscle tissue Present Regionally restricted S4E Heart Merged , S4E Heart CCAT Cytoplasmic and membranous expression in heart muscle.
Specimen S4E Blood vessels: embryonic day 11.5; Cacna1ctm1.2Red/Cacna1c+ (more )
Structure Level Pattern Image Note
TS19: blood vessel Present Regionally restricted S4E Blood vessels CCAT , S4E Blood vessels Merged Cytoplasmic and membranous expression in major blood vessels
Specimen S4E Head Mesenchyme: embryonic day 11.5; Cacna1ctm1.2Red/Cacna1c+ (more )
Structure Level Pattern Image Note
TS19: head mesenchyme Strong Regionally restricted S4E Head Mesenchyme Merged , S4E Head Mesenchyme CCAT Strong nuclear expression in mesenchymal cells.
Specimen S4E Liver: embryonic day 11.5; Cacna1ctm1.2Red/Cacna1c+ (more )
Structure Level Pattern Image Note
TS19: liver Absent S4E Liver Merged , S4E Liver CCAT Expression not detected in liver.
Specimen 5F Cav1.2 Null (upper): embryonic day 11.5; Cacna1ctm1.2Red/Cacna1ctm1.2Red (more )
Structure Level Pattern Image Note
TS19: somite Strong Regionally restricted 5F Cav1.2 Null CCAT (upper) Intact nuclear expression in somites
Specimen 5F Cav1.2 Null (lower): embryonic day 11.5; Cacna1ctm1.2Red/Cacna1ctm1.2Red (more )
Structure Level Pattern Image Note
TS19: somite Present Regionally restricted 5F Cav1.2 Null CCAT (lower) Intact nuclear expression in somites
Specimen 5F Wild Type (upper): embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: somite Strong Regionally restricted 5F Wild Type CCAT (upper) Strong nuclear expression in somites
Specimen 5F Wild Type (lower): embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: somite Strong Regionally restricted 5F Wild Type CCAT (lower) Strong nuclear expression in somites
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory