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Gene Expression Data
Assay Details
Assay
Reference: J:213418 Li D, et al., Formation of proximal and anterior limb skeleton requires early function of Irx3 and Irx5 and is negatively regulated by Shh signaling. Dev Cell. 2014 Apr 28;29(2):233-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7615145
Gene symbol: Casp3
Gene name: caspase 3
Results
Specimen S2G control: embryonic day 10.5 (more )
Note: 37-somite stage
Structure Level Pattern Image Note
TS17: hindlimb bud Present Regionally restricted S2G control Casp3 , S2G control merge Expressed in the most proximal portion.
Specimen S2G DKO: embryonic day 10.5; Irx3tm3.1Hui/Irx3tm3.1Hui, Irx5tm3Hui/Irx5tm3Hui (more )
Note: 37-somite stage
Structure Level Pattern Image Note
TS17: hindlimb bud Present Regionally restricted S2G DKO merge , S2G DKO Casp3 Increased expression in the most proximal portion.
Specimen not shown: embryonic day 9.75 (more )
Note: hindlimb bud initiation stage
Structure Level Pattern Image Note
TS16: hindlimb bud Absent
Specimen not shown: embryonic day 9.75; Irx3tm3.1Hui/Irx3tm3.1Hui, Irx5tm3Hui/Irx5tm3Hui (more )
Note: hindlimb bud initiation stage
Structure Level Pattern Image Note
TS16: hindlimb bud Absent Same as in the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory