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Gene Expression Data
Assay Details
Assay
Reference: J:333825 Lorenzana-Carrillo MA, et al., TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure. Sci Transl Med. 2022 Nov 2;14(669):eabm3565
Assay type: Western blot
MGI Accession ID: MGI:7580983
Gene symbol: Pkm
Gene name: pyruvate kinase, muscle
Antibody: Phospho-PKM2 (Tyr105) Antibody (3827)
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: The antibody used recognizes the phosphorylated form of the protein.
Results Image: 1A Y105P-PKM2
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
Brain P adult TS28: brain Present (a) C57BL/6N Not Specified
Lung P adult TS28: lung Present C57BL/6N Not Specified
Heart P adult TS28: heart Present (a) C57BL/6N Not Specified
Liver P adult TS28: liver Absent C57BL/6N Not Specified
Kidney P adult TS28: metanephros Present C57BL/6N Not Specified
Muscle P adult TS28: musculature Present (a) C57BL/6N Not Specified
Notes:
(a) Highest expression compared with other tissues.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory