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Gene Expression Data
Assay Details
Assay
Reference: J:181601 Bassett EA, et al., Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn. 2012 Apr;241(4):814-29
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7579039
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Antibody: anti-Otx2
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen S5C: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: photoreceptor layer photoreceptor cell Present S5C

Specimen S5D: postnatal day 0; Tfap2atm1Hsv/Tfap2atm1.1Hsv, Tfap2btm1Rbu/Tfap2btm1Rbu, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: photoreceptor layer photoreceptor cell Present S5D No difference in staining was observed in the mutant compared with control.

Specimen not shown P0: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: photoreceptor layer photoreceptor cell Present Otx2-positive photoreceptor cells were not co-labeled with Tfap2c.

Specimen not shown P7: postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: photoreceptor layer photoreceptor cell Present Otx2-positive photoreceptor cells were not co-labeled with Tfap2c.

Specimen not shown P21: postnatal day 21 (more )
Structure Cell Type Level Pattern Image Note
TS28: photoreceptor layer photoreceptor cell Present Otx2-positive photoreceptor cells were not co-labeled with Tfap2c.

Specimen not shown control: embryonic day 17.5 (more )
Structure Cell Type Level Pattern Image Note
TS25: neural retina photoreceptor cell Present

Specimen not shown mutant: embryonic day 17.5; Tfap2atm1Hsv/Tfap2atm1.1Hsv, Tfap2btm1Rbu/Tfap2btm1Rbu, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS25: neural retina photoreceptor cell Present No difference in staining was observed in the mutant compared with control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory