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Gene Expression Data
Assay Details
Assay
Reference: J:181601 Bassett EA, et al., Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn. 2012 Apr;241(4):814-29
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7579023
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: anti-C-Isl-1 protein (K5)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 8E: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: retina inner nuclear layer amacrine cell Present Regionally restricted 8E Expression was detected in a mosaic pattern of cholinergic amacrine cells.
Specimen 8F: embryonic day 18.5; Tfap2atm1Hsv/Tfap2atm1.1Hsv, Tfap2btm1Rbu/Tfap2btm1Rbu, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: retina inner nuclear layer amacrine cell Present Regionally restricted 8F Expression was detected in cholinergic amacrine cells in the mutant, but they did not exhibit the same regular arrangement of the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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