Gene Expression Data
Assay Details
Assay
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Reference:
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J:181601
Bassett EA, et al., Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn. 2012 Apr;241(4):814-29
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7579012
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Gene symbol:
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Sox2
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Gene name:
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SRY (sex determining region Y)-box 2
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Antibody:
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anti-Sox2
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Detection system:
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Secondary antibody coupled to Alexa Fluor 568
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Results
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Specimen
4K:
postnatal day 0
(more )
Note: Double labeled: red - Sox2; green - Tfap2c (assay MGI:7579003).
Specimen
4K:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Note:
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Double labeled: red - Sox2; green - Tfap2c (assay MGI:7579003).
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS27: neural retina |
amacrine cell |
Present |
Regionally restricted |
4K
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Expression was detected in cholinergic amacrine cells. There was no overlap with Tfap2c immunoreactivity.
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Specimen
4L:
postnatal day 0
(more )
Note: Double labeled: red - Sox2; green - Tfap2a (assay MGI:7578959).
Specimen
4L:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Note:
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Double labeled: red - Sox2; green - Tfap2a (assay MGI:7578959).
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS27: neural retina |
amacrine cell |
Present |
Regionally restricted |
4L
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Expression was detected in cholinergic amacrine cells. Expressed co-localized with Tfap2a.
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Specimen
4M:
postnatal day 0
(more )
Note: Double labeled: red - Sox2; green - Tfap2b (assay MGI:7578963).
Specimen
4M:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Note:
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Double labeled: red - Sox2; green - Tfap2b (assay MGI:7578963).
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS27: neural retina |
amacrine cell |
Present |
Regionally restricted |
4M
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Expression was detected in cholinergic amacrine cells. Expressed co-localized with Tfap2b.
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Specimen
8G:
embryonic day 18.5
(more )
Specimen
8G:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
8H:
(close )
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS26: retina ganglion cell layer |
amacrine cell |
Present |
Regionally restricted |
8H
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Expression was detected in cholinergic amacrine cells in the mutant, but the orderly distribution of the labeled cells was disrupted.
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TS26: retina inner nuclear layer |
amacrine cell |
Present |
Regionally restricted |
8H
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Expression was detected in cholinergic amacrine cells in the mutant, but the orderly distribution of the labeled cells was disrupted.
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Specimen
not shown P0:
postnatal day 0
(more )
Specimen
not shown P0:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS27: retina |
Mueller cell |
Present |
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Sox2-positive Muller glial cells were not co-labeled with Tfap2c.
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Specimen
not shown P7:
postnatal day 7
(more )
Specimen
not shown P7:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 7
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Sex:
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Not Specified
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Type:
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section
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Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS28: retina |
Mueller cell |
Present |
|
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Sox2-positive Muller glial cells were not co-labeled with Tfap2c.
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Specimen
not shown P21:
postnatal day 21
(more )
Specimen
not shown P21:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 21
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Sex:
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Not Specified
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Type:
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section
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Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS28: retina |
Mueller cell |
Present |
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Sox2-positive Muller glial cells were not co-labeled with Tfap2c.
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