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Gene Expression Data
Assay Details
Assay
Reference: J:181601 Bassett EA, et al., Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn. 2012 Apr;241(4):814-29
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7579011
Gene symbol: Bhlhe22
Gene name: basic helix-loop-helix family, member e22
Antibody: anti-BHLHB5 (E17; sc-6045)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 4H: postnatal day 0 (more )
Note: Double labeled: red - Bhlhe22; green - Tfap2c (assay MGI:7579003).
Structure Cell Type Level Pattern Image Note
TS27: neural retina GABAergic amacrine cell Present 4H Expression co-localized with Tfap2c.
Specimen 4I: postnatal day 0 (more )
Note: Double labeled: red - Bhlhe22; green - Tfap2a (assay MGI:7578959).
Structure Cell Type Level Pattern Image Note
TS27: neural retina GABAergic amacrine cell Present 4I Expression co-localized with Tfap2a.
Specimen 4J: postnatal day 0 (more )
Note: Double labeled: red - Bhlhe22; green - Tfap2b (assay MGI:7578963).
Structure Cell Type Level Pattern Image Note
TS27: neural retina GABAergic amacrine cell Present 4J Expression co-localized with Tfap2b.
Specimen 8C: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: retina inner nuclear layer GABAergic amacrine cell Present 8C
Specimen 8D: postnatal day 0; Tfap2atm1Hsv/Tfap2atm1.1Hsv, Tfap2btm1Rbu/Tfap2btm1Rbu, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: retina inner nuclear layer Ambiguous Regionally restricted 8D The band of immunopositive cells was not observed in mutants.
Specimen not shown control: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: neural retina GABAergic amacrine cell Present
Specimen not shown mutant: embryonic day 15.5; Tfap2atm1Hsv/Tfap2atm1.1Hsv, Tfap2btm1Rbu/Tfap2btm1Rbu, Tg(Pax6-cre,GFP)2Pgr/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS23: neural retina GABAergic amacrine cell Present The expression pattern was similar in mutant compared with control at E15.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory