Nefh Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:292124 Terenzio M, et al., DYNLRB1 is essential for dynein mediated transport and neuronal survival. Neurobiol Dis. 2020 Jul;140:104816
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7578905
Gene symbol:	Nefh
Gene name:	neurofilament, heavy polypeptide

Antibody:	anti-NFH
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

Specimen 2E wild type: postnatal adult (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: dorsal root ganglion	sensory neuron of dorsal root ganglion	Present		2E wild type NFH	Expression in proprioceptive neurons.

Specimen 2E RNX3-Dynlrb1-/-: postnatal adult; Dynlrb1^{tm1c(EUCOMM)Wtsi}/Dynlrb1^{tm1c(EUCOMM)Wtsi}, Runx3^{tm6(EGFP/cre)Yg}/Runx3⁺ (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS28: dorsal root ganglion	sensory neuron of dorsal root ganglion	Present		2E RNX3-Dynlrb1-/- NFH	Number of proprioceptive neurons greatly reduced compared to wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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