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Gene Expression Data
Assay Details
Assay
Reference: J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7550889
Gene symbol: Bcl11b
Gene name: B cell leukemia/lymphoma 11B
Antibody: anti-Bcl-11b (sc-56014, 25B6)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 7E: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 7E Expression was detected in middle to deep cerebral cortex layers.
TS28: dentate gyrus neuron Present 7E
TS28: hippocampus CA1 neuron Present 7E
TS28: hippocampus CA2 neuron Present 7E
TS28: hippocampus CA3 neuron Present 7E

Specimen 7F: postnatal adult; Emx1tm1(cre)Ito/Emx1+, Sox11tm1.1Vlf/Sox11tm1.1Vlf, Sox4tm1Vlf/Sox4tm1Vlf (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 7F Staining was disrupted in the cortex due to defects of cortical lamination in the conditional mutant.
TS28: hippocampus Absent 7F The mutant hippocampus was severely stunted or missing.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory