About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:329220 Chen Y, et al., Hnrnpk maintains chondrocytes survival and function during growth plate development via regulating Hif1alpha-glycolysis axis. Cell Death Dis. 2022 Sep 20;13(9):803
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7546921
Gene symbol: Mmp13
Gene name: matrix metallopeptidase 13
Antibody: anti-Mmp13 [EPR21778] (219620)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 2D WT: embryonic day 18.5; Hnrnpktm1.1Cya/Hnrnpktm1.1Cya (more )
Structure Cell Type Level Pattern Image Note
TS26: tibia growth plate cartilage chondrocyte Present Regionally restricted 2D WT Expression in late hypertrophic chondrocytes.
Specimen 2D CKO: embryonic day 18.5; Hnrnpktm1.1Cya/Hnrnpktm1.1Cya, Tg(Col2a1-cre)1Xya/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: tibia growth plate cartilage chondrocyte Strong 2D CKO Expression increased significantly compared with wild type, indicating premature differentiation of chondrocytes.
Specimen S2F WT: embryonic day 15.5; Hnrnpktm1.1Cya/Hnrnpktm1.1Cya (more )
Structure Level Pattern Image Note
TS23: tibia Present S2F WT
Specimen S2F CKO: embryonic day 15.5; Hnrnpktm1.1Cya/Hnrnpktm1.1Cya, Tg(Col2a1-cre)1Xya/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: tibia Weak S2F CKO Expression decreased compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory