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Gene Expression Data
Assay Details
Assay
Reference: J:293091 Li Z, et al., Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7544058
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Results
Specimen 2H fl/fl: embryonic day 16.5; H2az2tm1.1Hko/H2az2tm1.1Hko (more )
Note: Double labeled: red - Sox2; green - Aif1 (assay MGI:7544053).
Structure Cell Type Level Pattern Image Note
TS24: cerebral cortex neural progenitor cell Present Regionally restricted 2H fl/fl (center) , 2H fl/fl (right lower) , 2H fl/fl (left) , 2H fl/fl (right middle) Expression in basal neural progenitor cells.
Specimen 2H cKO: embryonic day 16.5; H2az2tm1.1Hko/H2az2tm1.1Hko, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: red - Sox2; green - Aif1 (assay MGI:7544053).
Structure Cell Type Level Pattern Image Note
TS24: cerebral cortex neural progenitor cell Present Regionally restricted 2H cKO (right middle) , 2H cKO (left) , 2H cKO (center) , 2H cKO (right lower) Contact between and neural progenitor cells in subventricular zone was enhanced compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
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