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Gene Expression Data
Assay Details
Assay
Reference: J:186504 Tanimoto Y, et al., Prevention of premature fusion of calvarial suture in GLI-Kruppel family member 3 (Gli3)-deficient mice by removing one allele of Runt-related transcription factor 2 (Runx2). J Biol Chem. 2012 Jun 15;287(25):21429-38
Assay type: RNA in situ
MGI Accession ID: MGI:7543950
Gene symbol: Bmp2
Gene name: bone morphogenetic protein 2
Probe: Bmp2 probe
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 6Aa: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: inter-parietal bone primordium Present Regionally restricted 6Aa Expressed in osteogenic fronts.
TS23: parietal bone Present Regionally restricted 6Aa Expressed in osteogenic fronts.
Specimen 6Ab: embryonic day 15.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS23: chondrocranium Present Regionally restricted 6Ab A slight increase in expression was observed in the mid-sutural mesenchymal cell layer.
TS23: inter-parietal bone primordium Present Regionally restricted 6Ab Expressed in osteogenic fronts.
TS23: parietal bone Present Regionally restricted 6Ab Expressed in osteogenic fronts.
Specimen 6Ac: embryonic day 15.5; Gli3Xt-J/Gli3Xt-J, Runx2tm1Mjo/Runx2+ (more )
Structure Level Pattern Image Note
TS23: inter-parietal bone primordium Present Regionally restricted 6Ac Expressed in osteogenic fronts, similar as in the wild-type.
TS23: parietal bone Present Regionally restricted 6Ac Expressed in osteogenic fronts, similar as in the wild-type.
Specimen 6Ba: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: frontal bone primordium Present Regionally restricted 6Ba Expressed in osteogenic fronts.
Specimen 6Bb: embryonic day 15.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS23: frontal bone primordium Present Regionally restricted 6Bb Expressed in osteogenic fronts
TS23: chondrocranium Strong Regionally restricted 6Bb Ectopically expressed intensely at the mid-sutural mesenchymal cell layer located away from osteogenic front.
Specimen 6Bc: embryonic day 15.5; Gli3Xt-J/Gli3Xt-J, Runx2tm1Mjo/Runx2+ (more )
Structure Level Pattern Image Note
TS23: frontal bone primordium Present Regionally restricted 6Bc Expressed in osteogenic fronts, similar as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory