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Gene Expression Data
Assay Details
Assay
Reference: J:186504 Tanimoto Y, et al., Prevention of premature fusion of calvarial suture in GLI-Kruppel family member 3 (Gli3)-deficient mice by removing one allele of Runt-related transcription factor 2 (Runx2). J Biol Chem. 2012 Jun 15;287(25):21429-38
Assay type: RNA in situ
MGI Accession ID: MGI:7543947
Gene symbol: Runx2
Gene name: runt related transcription factor 2
Probe: Runx2-I cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 5Ad: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: inter-parietal bone primordium Present Regionally restricted 5Ad Expressed in the osteogenic front.
TS23: parietal bone Present Regionally restricted 5Ad Expressed in the osteogenic front.
TS23: chondrocranium Present Regionally restricted 5Ad Expressed in the osteogenic fronts and sutural mesenchymal cells some distance from osteogenic fronts, especially around the parietal bone.
Specimen 5Ae: embryonic day 15.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS23: inter-parietal bone primordium Present Regionally restricted 5Ae Expressed in less intensity in the osteogenic front.
TS23: parietal bone Present Regionally restricted 5Ae Expressed in less intensity in the osteogenic front.
TS23: chondrocranium Present Regionally restricted 5Ae Expression in the sutural mesenchymal cells was similar as in the wild-type.
Specimen 5Af: embryonic day 15.5; Gli3Xt-J/Gli3Xt-J, Runx2tm1Mjo/Runx2+ (more )
Structure Level Pattern Image Note
TS23: parietal bone Present Regionally restricted 5Af Expressed in the osteogenic front, similar as in the wild-type.
TS23: chondrocranium Present Regionally restricted 5Af Expression in the sutural mesenchymal cells was similar as in the wild-type.
Specimen 5Bd: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: frontal bone primordium Present Regionally restricted 5Bd Expressed in the osteogenic front.
TS23: chondrocranium Present Regionally restricted 5Bd Expressed in the sutural mesenchymal cells.
Specimen 5Be: embryonic day 15.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS23: frontal bone primordium Present Regionally restricted 5Be Expressed in less intensity in the osteogenic front.
TS23: chondrocranium Present Regionally restricted 5Be Expression in the sutural mesenchymal cells was similar as in the wild-type.
Specimen 5Bf: embryonic day 15.5; Gli3Xt-J/Gli3Xt-J, Runx2tm1Mjo/Runx2+ (more )
Structure Level Pattern Image Note
TS23: frontal bone primordium Present Regionally restricted 5Bf Expressed in the osteogenic front, similar as in the wild-type.
TS23: chondrocranium Present Regionally restricted 5Bf Expression in the sutural mesenchymal cells was similar as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory