Gene Expression Data
Assay Details
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Assay
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Reference:
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J:288669
Wedel M, et al., Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation. Nucleic Acids Res. 2020 May 21;48(9):4839-4857
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7543401
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Gene symbol:
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Pdgfra
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Gene name:
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platelet derived growth factor receptor, alpha polypeptide
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Results
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Specimen
2Q:
embryonic day 14.5
(more  )
Specimen
2Q:
(close  )
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Genetic Background:
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involves: C3H * C57BL/6J
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS22: spinal cord |
oligodendrocyte precursor cell |
Present |
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2Q
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Specimen
2R:
embryonic day 16.5
(more )
Specimen
2R:
(close )
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Genetic Background:
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involves: C3H * C57BL/6J
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS24: spinal cord |
oligodendrocyte precursor cell |
Present |
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2R
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Specimen
2S:
embryonic day 18.5
(more )
Specimen
2S:
(close )
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Genetic Background:
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involves: C3H * C57BL/6J
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: spinal cord |
oligodendrocyte precursor cell |
Present |
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2S
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Specimen
2T:
(close )
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Genetic Background:
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involves: C3H * C57BL/6J * C57BL/6N
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Mutant Allele(s):
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Tcf4tm1a(EUCOMM)Wtsi/Tcf4tm1a(EUCOMM)Wtsi
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS22: spinal cord |
oligodendrocyte precursor cell |
Present |
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2T
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Expression in most oligodendroglial cells with number of expressing cells comparable to that of controls.
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Specimen
2U:
(close )
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Genetic Background:
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involves: C3H * C57BL/6J * C57BL/6N
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Mutant Allele(s):
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Tcf4tm1a(EUCOMM)Wtsi/Tcf4tm1a(EUCOMM)Wtsi
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS24: spinal cord |
oligodendrocyte precursor cell |
Present |
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2U
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Expression in most oligodendroglial cells with number of expressing cells comparable to that of controls.
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Specimen
2V:
(close )
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Genetic Background:
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involves: C3H * C57BL/6J * C57BL/6N
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Mutant Allele(s):
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Tcf4tm1a(EUCOMM)Wtsi/Tcf4tm1a(EUCOMM)Wtsi
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: spinal cord |
oligodendrocyte precursor cell |
Present |
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2V
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Expression in most oligodendroglial cells with number of expressing cells comparable to that of controls.
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Specimen
8C:
embryonic day 18.5
(more )
Specimen
8C:
(close )
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Genetic Background:
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involves: C3H * C57BL/6J
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: spinal cord |
oligodendrocyte precursor cell |
Present |
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8C
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Expression in most oligodendroglial cells with number of expressing cells comparable to that of controls.
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Specimen
8F:
(close )
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Genetic Background:
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involves: C3H * C57BL/6J * C57BL/6N
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Mutant Allele(s):
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Tcf4tm1a(EUCOMM)Wtsi/Tcf4+
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: spinal cord |
oligodendrocyte precursor cell |
Present |
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8F
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Expression in most oligodendroglial cells with number of expressing cells comparable to that of controls.
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Specimen
8I:
(close )
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Genetic Background:
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involves: C3H * C57BL/6J
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Mutant Allele(s):
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Olig2tm1(cre)Tmj/Olig2+
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: spinal cord |
oligodendrocyte precursor cell |
Present |
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8I
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Expression in most oligodendroglial cells with number of expressing cells comparable to that of controls.
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Specimen
8L:
(close )
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Genetic Background:
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involves: C3H * C57BL/6J * C57BL/6N
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Mutant Allele(s):
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Olig2tm1(cre)Tmj/Olig2+
Tcf4tm1a(EUCOMM)Wtsi/Tcf4+
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: spinal cord |
oligodendrocyte precursor cell |
Present |
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8L
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Expression in most oligodendroglial cells with number of expressing cells comparable to that of controls.
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Specimen
Sox10 het not shown:
embryonic day 18.5; Sox10tm1Weg/Sox10 +
(more )
Note: Data presented in Fig. 10G.
Specimen
Sox10 het not shown:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6J
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Mutant Allele(s):
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Sox10tm1Weg/Sox10+
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Data presented in Fig. 10G.
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: spinal cord |
spinal cord oligodendrocyte |
Present |
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No difference in numbers of expressing cells compared to wild type control.
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Specimen
ST double het not shown:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6J * C57BL/6N
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Mutant Allele(s):
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Sox10tm1Weg/Sox10+
Tcf4tm1a(EUCOMM)Wtsi/Tcf4+
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Data presented in Fig. 10G.
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: spinal cord |
oligodendrocyte precursor cell |
Present |
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No difference in numbers of expressing cells compared to wild type control.
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Analysis Tools