Gene Expression Data
Assay Details
Assay
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Reference:
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J:288669
Wedel M, et al., Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation. Nucleic Acids Res. 2020 May 21;48(9):4839-4857
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7543399
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Gene symbol:
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Olig2
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Gene name:
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oligodendrocyte transcription factor 2
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Results
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Specimen
2J:
embryonic day 14.5
(more )
Specimen
2J:
(close )
Genetic Background:
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involves: C3H * C57BL/6J
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Age:
|
embryonic day 14.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS22: spinal cord |
spinal cord oligodendrocyte |
Present |
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2J
|
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Specimen
2K:
embryonic day 16.5
(more )
Specimen
2K:
(close )
Genetic Background:
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involves: C3H * C57BL/6J
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Age:
|
embryonic day 16.5
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Sex:
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Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS24: spinal cord |
spinal cord oligodendrocyte |
Present |
|
2K
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Specimen
2L:
embryonic day 18.5
(more )
Specimen
2L:
(close )
Genetic Background:
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involves: C3H * C57BL/6J
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Age:
|
embryonic day 18.5
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Sex:
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Not Specified
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Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS26: spinal cord |
spinal cord oligodendrocyte |
Present |
|
2L
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Specimen
2M:
(close )
Genetic Background:
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involves: C3H * C57BL/6J * C57BL/6N
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Mutant Allele(s):
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Tcf4tm1a(EUCOMM)Wtsi/Tcf4tm1a(EUCOMM)Wtsi
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
|
optical section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS22: spinal cord |
spinal cord oligodendrocyte |
Present |
|
2M
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Number of expressing cells and their distribution throughout spinal cord appeared comparable to that of controls.
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Specimen
2N:
(close )
Genetic Background:
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involves: C3H * C57BL/6J * C57BL/6N
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Mutant Allele(s):
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Tcf4tm1a(EUCOMM)Wtsi/Tcf4tm1a(EUCOMM)Wtsi
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Age:
|
embryonic day 16.5
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Sex:
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Not Specified
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Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS24: spinal cord |
spinal cord oligodendrocyte |
Present |
|
2N
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Number of expressing cells and their distribution throughout spinal cord appeared comparable to that of controls.
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Specimen
2O:
(close )
Genetic Background:
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involves: C3H * C57BL/6J * C57BL/6N
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Mutant Allele(s):
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Tcf4tm1a(EUCOMM)Wtsi/Tcf4tm1a(EUCOMM)Wtsi
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Age:
|
embryonic day 18.5
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Sex:
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Not Specified
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Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS26: spinal cord |
spinal cord oligodendrocyte |
Present |
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2O
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Number of expressing cells and their distribution throughout spinal cord appeared comparable to that of controls.
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Specimen
8B:
embryonic day 18.5
(more )
Specimen
8B:
(close )
Genetic Background:
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involves: C3H * C57BL/6J
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Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS26: spinal cord |
spinal cord oligodendrocyte |
Present |
|
8B
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Number and localization of expressing cells completely identical among all genotypes analyzed.
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Specimen
8E:
(close )
Genetic Background:
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involves: C3H * C57BL/6J * C57BL/6N
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Mutant Allele(s):
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Tcf4tm1a(EUCOMM)Wtsi/Tcf4+
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Age:
|
embryonic day 18.5
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Sex:
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Not Specified
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Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS26: spinal cord |
spinal cord oligodendrocyte |
Present |
|
8E
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Number and localization of expressing cells completely identical among all genotypes analyzed.
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Specimen
8H:
(close )
Genetic Background:
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involves: C3H * C57BL/6J
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Mutant Allele(s):
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Olig2tm1(cre)Tmj/Olig2+
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
|
optical section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS26: spinal cord |
spinal cord oligodendrocyte |
Present |
|
8H
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Number and localization of expressing cells completely identical among all genotypes analyzed.
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Specimen
8K:
(close )
Genetic Background:
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involves: C3H * C57BL/6J * C57BL/6N
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Mutant Allele(s):
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Olig2tm1(cre)Tmj/Olig2+ Tcf4tm1a(EUCOMM)Wtsi/Tcf4+
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Age:
|
embryonic day 18.5
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Sex:
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Not Specified
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Type:
|
optical section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS26: spinal cord |
spinal cord oligodendrocyte |
Present |
|
8K
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Number and localization of expressing cells completely identical among all genotypes analyzed.
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Specimen
Sox10 het not shown:
embryonic day 18.5; Sox10tm1Weg/Sox10 +
(more )
Note: Data presented in Fig. 10F.
Specimen
Sox10 het not shown:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6J
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Mutant Allele(s):
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Sox10tm1Weg/Sox10+
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
|
optical section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
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Data presented in Fig. 10F.
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS26: spinal cord |
spinal cord oligodendrocyte |
Present |
|
|
No difference in numbers of expressing cells compared to wild type control.
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Specimen
ST double het not shown:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6J * C57BL/6N
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Mutant Allele(s):
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Sox10tm1Weg/Sox10+ Tcf4tm1a(EUCOMM)Wtsi/Tcf4+
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Age:
|
embryonic day 18.5
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Sex:
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Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Data presented in Fig. 10F.
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS26: spinal cord |
spinal cord oligodendrocyte |
Present |
|
|
No difference in numbers of expressing cells compared to wild type control.
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