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Gene Expression Data
Assay Details
Assay
Reference: J:288669 Wedel M, et al., Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation. Nucleic Acids Res. 2020 May 21;48(9):4839-4857
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7543399
Gene symbol: Olig2
Gene name: oligodendrocyte transcription factor 2
Results
Specimen 2J: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: spinal cord spinal cord oligodendrocyte Present 2J

Specimen 2K: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: spinal cord spinal cord oligodendrocyte Present 2K

Specimen 2L: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: spinal cord spinal cord oligodendrocyte Present 2L

Specimen 2M: embryonic day 14.5; Tcf4tm1a(EUCOMM)Wtsi/Tcf4tm1a(EUCOMM)Wtsi (more )
Structure Cell Type Level Pattern Image Note
TS22: spinal cord spinal cord oligodendrocyte Present 2M Number of expressing cells and their distribution throughout spinal cord appeared comparable to that of controls.

Specimen 2N: embryonic day 16.5; Tcf4tm1a(EUCOMM)Wtsi/Tcf4tm1a(EUCOMM)Wtsi (more )
Structure Cell Type Level Pattern Image Note
TS24: spinal cord spinal cord oligodendrocyte Present 2N Number of expressing cells and their distribution throughout spinal cord appeared comparable to that of controls.

Specimen 2O: embryonic day 18.5; Tcf4tm1a(EUCOMM)Wtsi/Tcf4tm1a(EUCOMM)Wtsi (more )
Structure Cell Type Level Pattern Image Note
TS26: spinal cord spinal cord oligodendrocyte Present 2O Number of expressing cells and their distribution throughout spinal cord appeared comparable to that of controls.

Specimen 8B: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: spinal cord spinal cord oligodendrocyte Present 8B Number and localization of expressing cells completely identical among all genotypes analyzed.

Specimen 8E: embryonic day 18.5; Tcf4tm1a(EUCOMM)Wtsi/Tcf4+ (more )
Structure Cell Type Level Pattern Image Note
TS26: spinal cord spinal cord oligodendrocyte Present 8E Number and localization of expressing cells completely identical among all genotypes analyzed.

Specimen 8H: embryonic day 18.5; Olig2tm1(cre)Tmj/Olig2+ (more )
Structure Cell Type Level Pattern Image Note
TS26: spinal cord spinal cord oligodendrocyte Present 8H Number and localization of expressing cells completely identical among all genotypes analyzed.

Specimen 8K: embryonic day 18.5; Olig2tm1(cre)Tmj/Olig2+, Tcf4tm1a(EUCOMM)Wtsi/Tcf4+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: spinal cord spinal cord oligodendrocyte Present 8K Number and localization of expressing cells completely identical among all genotypes analyzed.

Specimen Sox10 het not shown: embryonic day 18.5; Sox10tm1Weg/Sox10+ (more )
Note: Data presented in Fig. 10F.
Structure Cell Type Level Pattern Image Note
TS26: spinal cord spinal cord oligodendrocyte Present No difference in numbers of expressing cells compared to wild type control.

Specimen ST double het not shown: embryonic day 18.5; Sox10tm1Weg/Sox10+, Tcf4tm1a(EUCOMM)Wtsi/Tcf4+ (more )
Note: Data presented in Fig. 10F.
Structure Cell Type Level Pattern Image Note
TS26: spinal cord spinal cord oligodendrocyte Present No difference in numbers of expressing cells compared to wild type control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory