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Gene Expression Data
Assay Details
Assay
Reference: J:321979 Kurz J, et al., Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735
Assay type: RNA in situ
MGI Accession ID: MGI:7539499
Gene symbol: Tagln
Gene name: transgelin
Results
Specimen 2D control: embryonic day 18.5; Rbpjtm1Hon/? (more )
Note: Controls were littermates with no cre.
Structure Cell Type Level Pattern Image Note
TS26: ureteral smooth muscle layer smooth muscle cell Present 2D Tagln control
Specimen 2D Rbpj-cKO: embryonic day 18.5; Rbpjtm1Hon/Rbpjtm1Hon, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: ureteral smooth muscle layer smooth muscle cell Weak 2D Tagln Rbpj-cKO Expression was weakly reduced in the mutant compared with control.
Specimen 3C control: postnatal day 4; Rbpjtm1Hon/? (more )
Note: Controls were littermates with no cre.
Structure Level Pattern Image Note
TS28: ureteral smooth muscle layer Present 3C control Tagln
Specimen 3C Rbpj-cKO: postnatal day 4; Rbpjtm1Hon/Rbpjtm1Hon, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: ureteral smooth muscle layer Present 3C Rbpj-cKO Tagln Expression appeared unaffected in the mutant compared with control.
Specimen 3F control: postnatal day 14; Rbpjtm1Hon/? (more )
Note: Controls were littermates with no cre.
Structure Level Pattern Image Note
TS28: ureteral smooth muscle layer Present 3F control Tagln
Specimen 3F Rbpj-cKO: postnatal day 14; Rbpjtm1Hon/Rbpjtm1Hon, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: ureteral smooth muscle layer Weak 3F Rbpj-cKO Tagln Expression was strongly reduced in the mutant compared with control.
Specimen 4C E14.5 control: embryonic day 14.5; Rbpjtm1Hon/? (more )
Note: Controls were littermates with no cre.
Structure Level Pattern Image Note
TS22: ureteral mesenchyme Absent 4C control E14.5 Tagln
Specimen 4C E14.5 Rbpj-cKO: embryonic day 14.5; Rbpjtm1Hon/Rbpjtm1Hon, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: ureteral mesenchyme Absent 4C Rbpj-cKO E14.5 Tagln
Specimen 4C E15.5 control: embryonic day 15.5; Rbpjtm1Hon/? (more )
Note: Controls were littermates with no cre.
Structure Level Pattern Image Note
TS23: ureteral mesenchyme Present 4C control E15.5 Tagln Expression commenced at E15.5.
Specimen 4C E15.5 Rbpj-cKO: embryonic day 15.5; Rbpjtm1Hon/Rbpjtm1Hon, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: ureteral mesenchyme Weak 4C Rbpj-cKO E15.5 Tagln Expression was reduced in the mutant compared with control.
Specimen 4C E16.5 control: embryonic day 16.5; Rbpjtm1Hon/? (more )
Note: Controls were littermates with no cre.
Structure Level Pattern Image Note
TS24: ureteral mesenchyme Present 4C control E16.5 Tagln
Specimen 4C E16.5 Rbpj-cKO: embryonic day 16.5; Rbpjtm1Hon/Rbpjtm1Hon, Tbx18tm4(cre)Akis/Tbx18+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: ureteral mesenchyme Present 4C Rbpj-cKO E16.5 Tagln Expression was reduced in the mutant compared with control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/21/2024
MGI 6.23 		The Jackson Laboratory