About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:333559 Rupani DN, et al., Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling. Development. 2023 Jan 15;150(2):dev201097
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7539134
Gene symbol: Adgre1
Gene name: adhesion G protein-coupled receptor E1
Antibody: anti-F4/80 (D2S9R) (70076)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen S5A Control: postnatal day 2; Adartm1Knk/?, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Ptf1a+/? (more )
Note: Control is either non-Cre-expressing OR Adar1 heterozygous litter mate.
Structure Cell Type Level Pattern Image Note
TS27: pancreas macrophage Present S5A Control inset , S5A Control
Specimen S5A CYA: postnatal day 2; Adartm1Knk/Adartm1Knk, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Ptf1atm1.1(cre)Cvw/Ptf1a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: pancreas Present S5A CYA , S5A CYA inset Authors report a higher proportion of macrophages relative to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory