About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:333559 Rupani DN, et al., Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling. Development. 2023 Jan 15;150(2):dev201097
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7539133
Gene symbol: Ptprc
Gene name: protein tyrosine phosphatase receptor type C
Antibody: anti-CD45 (561018)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 3C E18.5 Control: embryonic day 18.5; Adartm1Knk/?, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Ptf1a+/? (more )
Note: Control is either non-Cre-expressing OR Adar1 heterozygous litter mate.
Structure Level Pattern Image Note
TS26: pancreas Present Regionally restricted 3C E18.5 Control inset , 3C E18.5 Control Expression in immune cells.
Specimen 3C E18.5 CYA: embryonic day 18.5; Adartm1Knk/Adartm1Knk, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Ptf1atm1.1(cre)Cvw/Ptf1a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: pancreas Present 3C E18.5 CYA , 3C E18.5 CYA inset
Specimen 3C P0 Control: postnatal day 0; Adartm1Knk/?, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Ptf1a+/? (more )
Note: Control is either non-Cre-expressing OR Adar1 heterozygous litter mate.
Structure Level Pattern Image Note
TS27: pancreas Present Regionally restricted 3C P0 Control , 3C P0 Control inset Expression in immune cells.
Specimen 3C P0 CYA: postnatal day 0; Adartm1Knk/Adartm1Knk, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Ptf1atm1.1(cre)Cvw/Ptf1a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: pancreas Strong Regionally restricted 3C P0 CYA inset , 3C P0 CYA Authors report an increase in immune cell abundance at P0 and P2.
Specimen 3C P2 Control: postnatal day 2; Adartm1Knk/?, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Ptf1a+/? (more )
Structure Level Pattern Image Note
TS27: pancreas Present Regionally restricted 3C P2 Control inset , 3C P2 Control Expression in immune cells.
Specimen 3C P2 CYA: postnatal day 2; Adartm1Knk/Adartm1Knk, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Ptf1atm1.1(cre)Cvw/Ptf1a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: pancreas Strong Regionally restricted 3C P2 CYA , 3C P2 CYA inset Authors report an increase in immune cell abundance at P0 and P2.
Specimen 3C P6 Control: postnatal day 6; Adartm1Knk/?, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Ptf1a+/? (more )
Structure Level Pattern Image Note
TS28: pancreas Present Regionally restricted 3C P6 Control , 3C P6 Control inset Expression in immune cells.
Specimen 3C P6 CYA: postnatal day 6; Adartm1Knk/Adartm1Knk, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Ptf1atm1.1(cre)Cvw/Ptf1a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: pancreas Strong Regionally restricted 3C P6 CYA inset , 3C P6 CYA
Specimen 3C P21 Control: postnatal day 21; Adartm1Knk/?, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Ptf1a+/? (more )
Structure Level Pattern Image Note
TS28: pancreas Present Regionally restricted 3C P21 Control , 3C P21 Control inset Expression in immune cells.
Specimen 3C P21 CYA: postnatal day 21; Adartm1Knk/Adartm1Knk, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Ptf1atm1.1(cre)Cvw/Ptf1a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: pancreas Strong Regionally restricted 3C P21 CYA , 3C P21 CYA inset
Specimen 4I Control: postnatal month 6; Adartm1Knk/Adar+, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Mavstm1Zjc/Mavstm1Zjc, Ptf1atm1.1(cre)Cvw/Ptf1a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: pancreas Present Regionally restricted 4I Control , 4I Control inset Expression in immune cells.
Specimen 4I CYAM: postnatal month 6; Adartm1Knk/Adartm1Knk, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Mavstm1Zjc/Mavstm1Zjc, Ptf1atm1.1(cre)Cvw/Ptf1a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: pancreas Present 4I CYAM inset , 4I CYAM Authors report no excess of immune infiltrate.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory