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Gene Expression Data
Assay Details
Assay
Reference: J:249803 Guerrero-Flores G, et al., Functional determination of the differentiation potential of ventral mesencephalic neural precursor cells during dopaminergic neurogenesis. Dev Biol. 2017 Sep 1;429(1):56-70
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7538898
Gene symbol: Lmx1a
Gene name: LIM homeobox transcription factor 1 alpha
Antibody: Anti-Lmx1a
Assay notes: Two antibodies were listed for Lmx1a: MGI:5707883 and MGI:7537353; the one used in this assay was not specified.
Results
Specimen E9.5: embryonic day 9.5 (more )
Note: Data not shown. Cell counts were graphed in Figure 1A.
Structure Cell Type Level Pattern Image Note
TS15: future midbrain neural progenitor cell Present Regionally restricted Expression was detected in the midbrain dopaminergic neural precursors.

Specimen E10.5: embryonic day 10.5 (more )
Note: Data not shown. Cell counts were graphed in Figure 1A.
Structure Cell Type Level Pattern Image Note
TS17: midbrain neural progenitor cell Present Regionally restricted Expression was detected in the midbrain dopaminergic neural precursors.

Specimen E11.5: embryonic day 11.5 (more )
Note: Data not shown. Cell counts were graphed in Figure 1A.
Structure Cell Type Level Pattern Image Note
TS19: midbrain neural progenitor cell Present Regionally restricted Expression was detected in the midbrain dopaminergic neural precursors.

Specimen E12.0: embryonic day 12.0 (more )
Note: Data not shown. Cell counts were graphed in Figure 1A.
Structure Cell Type Level Pattern Image Note
TS20: midbrain neural progenitor cell Present Regionally restricted Expression was detected in the midbrain dopaminergic neural precursors.

Specimen E12.5: embryonic day 12.5 (more )
Note: Data not shown. Cell counts were graphed in Figure 1A.
Structure Cell Type Level Pattern Image Note
TS20: midbrain neural progenitor cell Present Regionally restricted Expression was detected in the midbrain dopaminergic neural precursors.

Specimen S1A: embryonic day 12.5 (more )
Note: BrdU at E9.5. Double labeled: red - Lmx1a; green - BrdU.
Structure Cell Type Level Pattern Image Note
TS20: midbrain midbrain dopaminergic neuron Present S1A Lmx1a , S1A Merge top Few of the Lmx1a+ cells were double labeled with BrdU (injection at E9.5).

Specimen S1B: embryonic day 12.5 (more )
Note: BrdU at E10.5. Triple labeled: blue - Lmx1a; red - Sox2 (assay MGI:7538886); green - BrdU.
Structure Cell Type Level Pattern Image Note
TS20: midbrain midbrain dopaminergic neuron Present S1B Lmx1a , S1B Merge top

Specimen S2A left: embryonic day 10.5 (more )
Note: Double labeled: red - Lmx1a; green - Sox2 (assay MGI:7538886).
Structure Level Pattern Image Note
TS17: midbrain Present Regionally restricted S2A left Most cells in the Lmx1a+ domain were Sox2+.

Specimen S3A left: embryonic day 11.5 (more )
Note: Double labeled: red - Lmx1a; green - Sox2 (assay MGI:7538886).
Structure Level Pattern Image Note
TS19: midbrain Present Regionally restricted S3A left Several Sox2+ cells were noted in the Lmx1a+ domain.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory