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Gene Expression Data
Assay Details
Assay
Reference: J:198483 Finelli MJ, et al., Differential phosphorylation of Smad1 integrates BMP and neurotrophin pathways through Erk/Dusp in axon development. Cell Rep. 2013 May 30;3(5):1592-606
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7529729
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Results
Specimen S3D Control: embryonic day 10.5; H2az2Tg(Wnt1-cre)11Rth/0, Smad1tm1Abr/Smad1+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS17: trigeminal ganglion peripheral sensory neuron Present Regionally restricted S3D Control Expression in peripheral axon projections of trigeminal ganglion neurons.
Specimen S3D cKO-Wnt1: embryonic day 10.5; H2az2Tg(Wnt1-cre)11Rth/0, Smad1tm1Abr/Smad1tm1.1Abr (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS17: trigeminal ganglion peripheral sensory neuron Present Regionally restricted S3D cKO-Wnt1 Expression in peripheral axon projections of trigeminal ganglion neurons.
Specimen S4A Control: embryonic day 11.5; H2az2Tg(Wnt1-cre)11Rth/0, Smad1tm1Abr/Smad1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: trigeminal nerve mandibular division Present S4A Control
TS19: trigeminal nerve maxillary division Present S4A Control
TS19: trigeminal nerve ophthalmic division Present S4A Control
Specimen S4A cKO-Wnt1: embryonic day 11.5; H2az2Tg(Wnt1-cre)11Rth/0, Smad1tm1Abr/Smad1tm1.1Abr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: trigeminal nerve mandibular division Present S4A cKO-Wnt1 Peripheral axons initiated in correct directions and with axonal lengths similar to controls.
TS19: trigeminal nerve maxillary division Present S4A cKO-Wnt1 Peripheral axons initiated in correct directions and with axonal lengths similar to controls.
TS19: trigeminal nerve ophthalmic division Present S4A cKO-Wnt1 Peripheral axons initiated in correct directions and with axonal lengths similar to controls.
Specimen S4B Control: embryonic day 12.5; H2az2Tg(Wnt1-cre)11Rth/0, Smad1tm1Abr/Smad1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: mystacial pad Present Regionally restricted S4B Control Expression axonal projections.
TS20: trigeminal nerve Present Regionally restricted S4B Control Expression axonal projections.
Specimen S4B cKO-Wnt1: embryonic day 12.5; H2az2Tg(Wnt1-cre)11Rth/0, Smad1tm1Abr/Smad1tm1.1Abr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: mystacial pad Present Regionally restricted S4B cKO-Wnt1 Axonal projection length, fasciculation and branching patterms similar to control.
TS20: trigeminal nerve Present Regionally restricted S4B cKO-Wnt1 Axonal projection length, fasciculation and branching patterms similar to control.
Specimen S4C Control: embryonic day 12.5; H2az2Tg(Wnt1-cre)11Rth/0, Smad1tm1Abr/Smad1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: forelimb nerve Present Regionally restricted S4C Control Expression axonal projections.
Specimen S4C cKO-Wnt1: embryonic day 12.5; H2az2Tg(Wnt1-cre)11Rth/0, Smad1tm1Abr/Smad1tm1.1Abr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: forelimb nerve Present Regionally restricted S4C cKO-Wnt1 Axonal projection length, fasciculation and branching patterms similar to control.
Specimen S4D Control: embryonic day 12.5; H2az2Tg(Wnt1-cre)11Rth/0, Smad1tm1Abr/Smad1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: trunk nerve Present Regionally restricted S4D Control Expression in superficial peripheral nerve projections.
Specimen S4D cKO-Wnt1: embryonic day 12.5; H2az2Tg(Wnt1-cre)11Rth/0, Smad1tm1Abr/Smad1tm1.1Abr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: trunk nerve Present Regionally restricted S4D cKO-Wnt1 Axonal projection length, fasciculation and branching patterms similar to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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