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Gene Expression Data
Assay Details
Assay
Reference: J:198483 Finelli MJ, et al., Differential phosphorylation of Smad1 integrates BMP and neurotrophin pathways through Erk/Dusp in axon development. Cell Rep. 2013 May 30;3(5):1592-606
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7529719
Gene symbol: Smad1
Gene name: SMAD family member 1
Antibody: anti-pSmad1L
Results
Specimen 6A +/+: postnatal day 1 (more )
Structure Cell Type Level Pattern Image Note
TS27: dorsal root ganglion sensory neuron of dorsal root ganglion Present 6A +/+ Expression in nuclei of neurons from E12.5 to P1.
Specimen 6A L/L: postnatal day 1; Smad1tm2Sor/Smad1tm2Sor (more )
Structure Level Pattern Image Note
TS27: dorsal root ganglion Absent 6A L/L Expression absent in mutant.
Specimen 6B Control: postnatal day 1; Smad1tm1Abr/Smad1+, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: dorsal root ganglion sensory neuron of dorsal root ganglion Present 6B Control Expression in nuclei of neurons from E12.5 to P1.
Specimen 6B cKO: postnatal day 1; Smad1tm1Abr/Smad1tm1.1Abr, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: dorsal root ganglion Absent 6B cKO Expression absent in mutant
Specimen S6F pSmad1L: postnatal day 1 (more )
Structure Cell Type Level Pattern Image Note
TS27: peripheral nerve Schwann cell Absent S6F pSMAD1L No expression in Schwann cells.
Specimen S6G pSmad1L: postnatal day 1 (more )
Note: Double labeled: red - Smad1; green - Tubb3 (assay MGI:7529721).
Structure Cell Type Level Pattern Image Note
TS27: dorsal root ganglion sensory neuron of dorsal root ganglion Present S6G Expression only detectable in neurons.
TS27: peripheral nerve Schwann cell Absent S6G No expression in Schwann cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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