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Gene Expression Data
Assay Details
Assay
Reference: J:240055 Grond S, et al., Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation. J Invest Dermatol. 2017 Feb;137(2):403-413
Assay type: Western blot
MGI Accession ID: MGI:7529166
Gene symbol: Flg
Gene name: filaggrin
Results
Image: 1i FLG ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Size Not Specified (b) Size Not Specified (c) Genetic BackgroundMutant Allele(s)Sex Note
flox/flox 1 P newborn TS27: epidermis Present Present Present involves: 129P2/OlaHsd Abhd5tm1Rze/Abhd5tm1RzeNot Specified
flox/flox 2 P newborn TS27: epidermis Present Present Present involves: 129P2/OlaHsd Abhd5tm1Rze/Abhd5tm1RzeNot Specified
flox/flox 3 P newborn TS27: epidermis Present Present Present involves: 129P2/OlaHsd Abhd5tm1Rze/Abhd5tm1RzeNot Specified
epid-/- 1 P newborn TS27: epidermis Strong (d) Strong (d) Weak (e) involves: 129P2/OlaHsd Abhd5tm1Rze/Abhd5tm1Rze, Tg(KRT14-cre)1Efu/0Not Specified Conditional mutant.
epid-/- 2 P newborn TS27: epidermis Strong (d) Strong (d) Present (e) involves: 129P2/OlaHsd Abhd5tm1Rze/Abhd5tm1Rze, Tg(KRT14-cre)1Efu/0Not Specified Conditional mutant.
epid-/- 3 P newborn TS27: epidermis Strong (d) Strong (d) Present (e) involves: 129P2/OlaHsd Abhd5tm1Rze/Abhd5tm1Rze, Tg(KRT14-cre)1Efu/0Not Specified Conditional mutant.
Notes:
(a) 3FLG
(b) 2FLG
(c) 1FLG
(d) Increased abundance of multimeric, nonprocessed units compared with the control.
(e) Reduced abundance of active, monomeric units compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory