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Targeted Allele Detail
Symbol: Abhd5tm1Rze
Name: abhydrolase domain containing 5; targeted mutation 1, Rudolf Zechner
MGI ID: MGI:5502402
Synonyms: CGI-58flox
Gene: Abhd5  Location: Chr9:122180681-122210589 bp, + strand  Genetic Position: Chr9, 73.03 cM, cytoband F4
Alliance: Abhd5tm1Rze page
Germline Transmission:  Earliest citation of germline transmission: J:160725
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA loxP site was inserted upstream of exon 4 and a floxed neo cassette was inserted downstream of exon 7. (J:160725)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Abhd5 Mutation:  11 strains or lines available
Original:  J:160725 Radner FP, et al., Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58). J Biol Chem. 2010 Mar 5;285(10):7300-11
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory