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Gene Expression Data
Assay Details
Assay
Reference: J:240055 Grond S, et al., Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation. J Invest Dermatol. 2017 Feb;137(2):403-413
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7529161
Gene symbol: Flg
Gene name: filaggrin
Results
Specimen 1h flox/flox: postnatal newborn; Abhd5tm1Rze/Abhd5tm1Rze (more )
Structure Cell Type Level Pattern Image Note
TS27: epidermis keratinocyte Present 1h FLG left Expressed in terminally differentiated keratinocytes.

Specimen 1h epid-/-: postnatal newborn; Abhd5tm1Rze/Abhd5tm1Rze, Tg(KRT14-cre)1Efu/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: epidermis keratinocyte Weak 1h FLG right Reduced expression in terminally differentiated keratinocytes, compared with the control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory