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Gene Expression Data
Assay Details
Assay
Reference: J:339296 Fries M, et al., Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections. Cell Rep. 2023 Aug 16;42(8):112985
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7525630
Gene symbol: Atoh7
Gene name: atonal bHLH transcription factor 7
Results
Specimen 1F E14.5 ATOH7: embryonic day 14.5 (more )
Note: Double labeled: magenta - Atoh7; green - Pou3f1 (assay MGI:7525611).
Structure Cell Type Level Pattern Image Note
TS22: retina retinal ganglion cell Present 1F E14.5 ATOH7 , 1F E14.5 (merged)
Specimen 1F E17.5 ATOH7: embryonic day 17.5 (more )
Note: Double labeled: magenta - Atoh7; green - Pou3f1 (assay MGI:7525611).
Structure Level Pattern Image Note
TS25: retina Present 1F E17.5 ATOH7 , 1F E17.5 (merged)
Specimen 1F P0 ATOH7: postnatal day 0 (more )
Note: Double labeled: magenta - Atoh7; green - Pou3f1 (assay MGI:7525611).
Structure Level Pattern Image Note
TS27: retina Present 1F P0 (merged) , 1F P0 ATOH7
Specimen S5B Pou3f1+/-: embryonic day 14.5; Pou3f1tm1Mejr/Pou3f1+ (more )
Structure Cell Type Level Pattern Image Note
TS22: retina retinal ganglion cell Present S5B Pou3f1+/- ATOH7
Specimen S5B Pou3f1-/-: embryonic day 14.5; Pou3f1tm1Mejr/Pou3f1tm1Mejr (more )
Structure Cell Type Level Pattern Image Note
TS22: retina retinal ganglion cell Present S5B Pou3f1-/- ATOH7 No difference in number of retinal ganglion cells compared to heterozygous embryos at E14.5.
Specimen 3A Pou3f1+/- ATOH7: embryonic day 17.5; Pou3f1tm1Mejr/Pou3f1+ (more )
Structure Cell Type Level Pattern Image Note
TS25: retina retinal ganglion cell Present 3A Pou3f1+/- ATOH7
Specimen 3A Pou3f1-/- ATOH7: embryonic day 17.5; Pou3f1tm1Mejr/Pou3f1tm1Mejr (more )
Structure Cell Type Level Pattern Image Note
TS25: retina retinal ganglion cell Present Regionally restricted 3A Pou3f1-/- ATOH7 Increase in propottion of expressing cells in retinal ganglion cell layer in central retina.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory