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Gene Expression Data
Assay Details
Assay
Reference: J:92061 Eng SR, et al., Coordinated regulation of gene expression by Brn3a in developing sensory ganglia. Development. 2004 Aug;131(16):3859-70
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7521970
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-TH
Results
Specimen 2D TH: embryonic day 13.5 (more )
Note: Double labeled: green - Th; red - Pou4f1 (assay MGI:7521967).
Structure Level Pattern Image Note
TS21: trigeminal ganglion Present Regionally restricted 2E Expression in limited subset of trigeminal neurons, most of which also express Pou4f1.
Specimen 2F TH +/+: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: trigeminal ganglion Present Regionally restricted 2F TH +/+ Expression in limited subset of trigeminal neurons, most of which also express Pou4f1.
Specimen 2F TH -/-: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Structure Level Pattern Image Note
TS21: trigeminal ganglion Weak 2F TH -/- Expression significantly decreased compared to control.
Specimen TH +/+ not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present
TS21: spinal cord Present Regionally restricted Expression in dorsal spinal cord.
Specimen TH -/- not shown: embryonic day 13.5; Pou4f1tm1Nat/Pou4f1tm1Nat (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present No significant changes in expression compared to wild type.
TS21: spinal cord Present Regionally restricted No change in expression in dorsal spinal cord compared to control.
Specimen 4L/M: embryonic day 13.5 (more )
Note: Double labeled: green - Th; red - Pou4f1 (assay MGI:7521967).
Structure Level Pattern Image Note
TS21: central nervous system Present Regionally restricted 4L , 4M No co-expression with Pou4f1 in central nervous system.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory