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Gene Expression Data
Assay Details
Assay
Reference: J:215514 Saulnier A, et al., The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Cereb Cortex. 2013 Nov;23(11):2552-67
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7518828
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase-3 (Asp175) (#9661)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen S5A Dmrt5+/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: telencephalon Present Regionally restricted S5A Dmrt5+/+ , S5A' Dmrt5+/+ Prominent cell death was noted in the roof plate. Apoptotic cells were absent in the dorsomedial part of the telencephalon.

Specimen S5A Dmrt5-/-: embryonic day 9.5; Dmrta2tm1Ejbd/Dmrta2tm1Ejbd (more )
Structure Level Pattern Image Note
TS15: telencephalon Present Regionally restricted S5A' Dmrt5-/- , S5A Dmrt5-/- Prominent cell death was noted in the roof plate. Apoptotic cells were absent in the dorsomedial part of the telencephalon.

Specimen S5B Dmrt5+/+: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon Absent S5B' Dmrt5+/+ , S5B Dmrt5+/+

Specimen S5B Dmrt5-/-: embryonic day 11.5; Dmrta2tm1Ejbd/Dmrta2tm1Ejbd (more )
Structure Level Pattern Image Note
TS19: telencephalon Absent S5B' Dmrt5-/- , S5B Dmrt5-/-

Specimen S5C Dmrt5+/+: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: telencephalon Absent S5C' Dmrt5+/+ , S5C Dmrt5+/+

Specimen S5C Dmrt5-/-: embryonic day 14.5; Dmrta2tm1Ejbd/Dmrta2tm1Ejbd (more )
Structure Level Pattern Image Note
TS22: telencephalon Absent S5C Dmrt5-/- , S5C' Dmrt5-/-


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/24/2026
MGI 6.24
The Jackson Laboratory