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Gene Expression Data
Assay Details
Assay
Reference: J:229010 Wang J, et al., Yap and Taz play a crucial role in neural crest-derived craniofacial development. Development. 2016 Feb 1;143(3):504-15
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7518687
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: MEC 13.3
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4A: embryonic day 10.5 (more )
Note: Double labeled: green - Pecam1; red - Acta2 (assay MGI:7518704).
Structure Level Pattern Image Note
TS17: blood vessel Present 4A

Specimen 4B: embryonic day 10.5; Wwtr1tm1.1Eno/Wwtr1tm1.1Eno, Yap1tm1.1Eno/Yap1tm1.1Eno, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - Acta2 (assay MGI:7518704).
Structure Level Pattern Image Note
TS17: blood vessel Present 4C , 4B This mutant had wrapped vessels around the hemangioma in the branchial arch.

Specimen 4D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: brain vascular element Present 4D

Specimen 4E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: brain vascular element Present 4E

Specimen 4F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: brain vascular element Present 4F

Specimen 4G: embryonic day 10.5; Wwtr1tm1.1Eno/Wwtr1tm1.1Eno, Yap1tm1.1Eno/Yap1tm1.1Eno, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: brain vascular element Present Regionally restricted 4G This mutant had vessel regression and disorganization compared to controls.

Specimen 4H: embryonic day 10.5; Wwtr1tm1.1Eno/Wwtr1tm1.1Eno, Yap1tm1.1Eno/Yap1tm1.1Eno, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: brain vascular element Present Regionally restricted 4H This mutant had vessel regression and disorganization compared to controls.

Specimen 4I: embryonic day 10.5; Wwtr1tm1.1Eno/Wwtr1tm1.1Eno, Yap1tm1.1Eno/Yap1tm1.1Eno, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: brain vascular element Present Regionally restricted 4I This mutant had vessel regression and disorganization compared to controls.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory