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Gene Expression Data
Assay Details
Assay
Reference: J:107401 Jadrich JL, et al., The TGF{beta} activated kinase TAK1 regulates vascular development in vivo. Development. 2006 Apr;133(8):1529-41
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7517204
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: anti-PECAM
Results
Specimen 5A: embryonic day 9.5; Map3k7Gt(XB444)Byg/Map3k7+ (more )
Structure Level Pattern Image Note
TS15: blood vessel Present 5A
TS15: endocardial lining Present 5A
Specimen 5B: embryonic day 9.5; Map3k7Gt(XB444)Byg/Map3k7Gt(XB444)Byg (more )
Structure Level Pattern Image Note
TS15: endocardial lining Present 5B Expression in this mutant was the same as in wild-type embryos.
TS15: blood vessel Present 5B
Specimen 5C: embryonic day 9.5; Map3k7Gt(XB444)Byg/Map3k7Gt(XB444)Byg (more )
Structure Level Pattern Image Note
TS15: blood vessel Present 5C
TS15: dorsal aorta Present Regionally restricted 5C Expression indicated that the anterior dorsal aorta appeared collapsed and discontinuous compared to wild-type.
TS15: branchial arch artery Present Regionally restricted 5C Expression indicated that the branchial arch artery appeared collapsed and discontinuous compared to wild-type.
Specimen 5D: embryonic day 9.5; Map3k7Gt(XB444)Byg/Map3k7+ (more )
Structure Level Pattern Image Note
TS15: head blood vessel Present 5D
Specimen 5E: embryonic day 9.5; Map3k7Gt(XB444)Byg/Map3k7+ (more )
Structure Level Pattern Image Note
TS15: head blood vessel Present Regionally restricted 5E Expression indicated severe dilation of the cranial vasculature in this mutant compared to wild-type.
Specimen 5F: embryonic day 9.5; Map3k7Gt(XB444)Byg/Map3k7+ (more )
Structure Level Pattern Image Note
TS15: head blood vessel Present Regionally restricted 5F Expression indicated severe dilation of the cranial vasculature in this mutant compared to wild-type.
Specimen 5G: embryonic day 9.5; Map3k7Gt(XB444)Byg/Map3k7+ (more )
Structure Level Pattern Image Note
TS15: dorsal aorta Present 5G
Specimen 5H: embryonic day 9.5; Map3k7Gt(XB444)Byg/Map3k7Gt(XB444)Byg (more )
Structure Level Pattern Image Note
TS15: dorsal aorta Present Regionally restricted 5H Expression in this mutant indicated lack of integrity of the dorsal aorta compared to wild-type.
Specimen 5I: embryonic day 9.5; Map3k7Gt(XB444)Byg/Map3k7Gt(XB444)Byg (more )
Structure Level Pattern Image Note
TS15: dorsal aorta Present Regionally restricted 5I Expression in this mutant indicated lack of integrity of the dorsal aorta compared to wild-type.
Specimen 5J: embryonic day 10.5; Map3k7Gt(XB444)Byg/Map3k7+ (more )
Structure Level Pattern Image Note
TS17: blood vessel Present 5J
Specimen 5K: embryonic day 10.5; Map3k7Gt(XB444)Byg/Map3k7Gt(XB444)Byg (more )
Structure Level Pattern Image Note
TS17: dorsal aorta Present Regionally restricted 5K In this mutant both the anterior and posterior dorsal aorta appeared collapsed compared to wild-type.
TS17: blood vessel Present 5K
Specimen S1C: embryonic day 8.5; Map3k7Gt(XB444)Byg/Map3k7+ (more )
Structure Level Pattern Image Note
TS13: dorsal aorta Present S1C
TS13: vascular system Present S1C
Specimen S1D: embryonic day 8.5; Map3k7Gt(XB444)Byg/Map3k7Gt(XB444)Byg (more )
Structure Level Pattern Image Note
TS13: dorsal aorta Present S1D In this mutant the vasculature including the dorsal aorta is the same as in wild-type.
TS13: vascular system Present S1D In this mutant the vasculature including the dorsal aorta is the same as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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