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Gene Expression Data
Assay Details
Assay
Reference: J:338080 Zhou X, et al., Trophoblast PR-SET7 dysfunction induces viral mimicry response and necroptosis associated with recurrent miscarriage. Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2216206120
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7516307
Gene symbol: H2ax
Gene name: H2A.X variant histone
Results
Specimen 1E gammH2AX Pr-set7f/f: embryonic day 5.25; Kmt5atm1.1Dare/Kmt5atm1.1Dare (more )
Structure Level Pattern Image Note
TS7: extraembryonic ectoderm Ambiguous 1E gammaH2AX Pr-set7f/f Expression in control not described
Specimen 1E gammH2AX Pr-set7fd/d: embryonic day 5.25; Elf5em1(cre)Jilu/Elf5+, Kmt5atm1.1Dare/Kmt5atm1.1Dare (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS7: extraembryonic ectoderm trophoblast cell Strong Widespread 1E gammaH2AX Pr-set7d/d Authors report massive DNA damage in trophoblasts in extraembryonic ectoderm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory