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Gene Expression Data
Assay Details
Assay
Reference: J:338080 Zhou X, et al., Trophoblast PR-SET7 dysfunction induces viral mimicry response and necroptosis associated with recurrent miscarriage. Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2216206120
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7516306
Gene symbol: Pou5f1
Gene name: POU domain, class 5, transcription factor 1
Results
Specimen 1D OCT4 Pr-set7f/f: embryonic day 5.5; Kmt5atm1.1Dare/Kmt5atm1.1Dare (more )
Structure Level Pattern Image Note
TS7: epiblast Present 1D OCT4 Pr-set7f/f

Specimen 1D OCT4 Pr-set7fd/d: embryonic day 5.5; Elf5em1(cre)Jilu/Elf5+, Kmt5atm1.1Dare/Kmt5atm1.1Dare (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS7: epiblast Present Regionally restricted 1D OCT4 Pr-set7d/d Expression remains but with abrupt localization.

Specimen S1C OCT4 Pr-set7f/f: embryonic day 6.5; Kmt5atm1.1Dare/Kmt5atm1.1Dare (more )
Note: Double labeled: red - Pou5f1; green - Tfap2c (assay MGI:7516305).
Structure Level Pattern Image Note
TS9: embryo Present Regionally restricted S1C AP-2gamma/OCT4 Pr-set7f/f , S1C OCT4 Pr-set7f/f Expression in epiblast.

Specimen S1C OCT4 Pr-set7fd/d: embryonic day 6.5; Elf5em1(cre)Jilu/Elf5+, Kmt5atm1.1Dare/Kmt5atm1.1Dare (more )
Note: Conditional mutant. Double labeled: red - Pou5f1; green - Tfap2c (assay MGI:7516305).
Structure Level Pattern Image Note
TS9: embryo Present Regionally restricted S1C OCT4 Pr-set7d/d , S1C AP-2gamma/OCT4 Pr-set7d/d Expression remains but with abrupt localization.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory