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Gene Expression Data
Assay Details
Assay
Reference: J:332104 Company V, et al., Adhesion molecule Amigo2 is involved in the fasciculation process of the fasciculus retroflexus. Dev Dyn. 2022 Nov;251(11):1834-1847
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7514832
Gene symbol: Cntn2
Gene name: contactin 2
Antibody: anti-Cntn2/TAG1 (AF4439)
Detection system: horseradish peroxidase
Results
Specimen 2D: embryonic day 11.5 (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS19: diencephalon Absent 2D

Specimen 2E: embryonic day 13.5 (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS21: habenula Present Regionally restricted 2E Expressed in the prospective medial habenular nucleus territory.
TS21: white matter Present Regionally restricted 2E Expressed in the fasciculus retroflexus.

Specimen 2F: embryonic day 15.5 (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS23: medial habenular nucleus Present Regionally restricted 2F Expression concentrated in the periventricular stratum.
TS23: fasciculus retroflexus Present 2F

Specimen 3G: embryonic day 18.5 (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS26: fasciculus retroflexus Present Regionally restricted 3G The medial habenular fasciculus retroflexus reached the rhombomere 1.

Specimen 3H: embryonic day 18.5; Amigo2tm1Lti/Amigo2tm1Lti (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS26: interpeduncular nucleus Present Regionally restricted 3H Positive medial habenular fasciculus retroflexus axons innervated the rostral and caudal region.

Specimen 3I: embryonic day 18.5 (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS26: fasciculus retroflexus Present Regionally restricted 3I A wider fasciculus retroflexus was observed following the expected trajectory.

Specimen 3J: embryonic day 18.5; Amigo2tm1Lti/Amigo2tm1Lti (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS26: interpeduncular nucleus Present Regionally restricted 3J Positive medial habenular fasciculus retroflexus axons innervated the rostral and caudal region, similar as in the wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory