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Gene Expression Data
Assay Details
Assay
Reference: J:175773 Maxwell MM, et al., The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS. Hum Mol Genet. 2011 Oct 15;20(20):3986-96
Assay type: Western blot
MGI Accession ID: MGI:7511724
Gene symbol: Sirt2
Gene name: sirtuin 2
Antibody: Anti-Sirt2 S8447
Detection system: Secondary antibody coupled to horseradish peroxidase
Results Image: 2A upper
 Sample Information Bands Other Sample Information
Lane AgeStructure 43 kDa (a) 39 kb (b) Genetic BackgroundMutant Allele(s)Sex Note
Cortex P m 5 TS28: cerebral cortex Present Very strong C57BL/6J Not Specified 3 ug total protein
Cortex P m 5 TS28: cerebral cortex Present Very strong C57BL/6J Not Specified 3 ug total protein
Striatum P m 5 TS28: corpus striatum Present Very strong C57BL/6J Not Specified 3 ug total protein
Striatum P m 5 TS28: corpus striatum Present Very strong C57BL/6J Not Specified 3 ug total protein
Sp. Cord P m 5 TS28: spinal cord Present Very strong C57BL/6J Not Specified 3 ug total protein
Sp. Cord P m 5 TS28: spinal cord Present Very strong C57BL/6J Not Specified 3 ug total protein
Heart P m 5 TS28: heart Present Present C57BL/6J Not Specified 15 ug total protein
Heart P m 5 TS28: heart Present Present C57BL/6J Not Specified 15 ug total protein
Liver P m 5 TS28: liver Present Present C57BL/6J Not Specified 15 ug total protein
Liver P m 5 TS28: liver Present Present C57BL/6J Not Specified 15 ug total protein
Kidney P m 5 TS28: metanephros Present Present C57BL/6J Not Specified 15 ug total protein
Kidney P m 5 TS28: metanephros Present Present C57BL/6J Not Specified 15 ug total protein
Sk. Musc P m 5 TS28: skeletal muscle Present Present C57BL/6J Not Specified 15 ug total protein
Sk. Musc P m 5 TS28: skeletal muscle Present Present C57BL/6J Not Specified 15 ug total protein
Notes:
(a) Sirt2.1 isoform predominates in the skeletal muscle.
(b) Sirt2.2 isoform was expressed at extremely high levels in the CNS.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory