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Gene Expression Data
Assay Details
Assay
Reference: J:210131 Roy A, et al., Lhx2 regulates the development of the forebrain hem system. Cereb Cortex. 2014 May;24(5):1361-72
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7511704
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki67
Results
Specimen 4F Control: embryonic day 12.5 (more )
Note: Double labeled: red - Mki67; green - BrdU.
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 4F Control Expressed in the septum.

Specimen 4F -/-: embryonic day 12.5; Lhx2tm1Dra/Lhx2tm1Dra (more )
Note: Double labeled: red - Mki67; green - BrdU.
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 4F -/- The quit fraction (BrdU+; Ki67- cells/total BrdU+ cells) was significantly greater in the mutant septum.

Specimen 4L Control: embryonic day 12.5 (more )
Note: Double labeled: red - Mki67; green - BrdU.
Structure Level Pattern Image Note
TS20: cortical hem Present 4L Control

Specimen 4L -/-: embryonic day 12.5; Lhx2tm1Dra/Lhx2tm1Dra (more )
Note: Double labeled: red - Mki67; green - BrdU.
Structure Level Pattern Image Note
TS20: cortical hem Present 4L -/- The quit fraction (BrdU+; Ki67- cells/total BrdU+ cells) was significantly greater in the mutant.

Specimen 5H Control: embryonic day 12.5 (more )
Note: Double labeled: red - Mki67; green - BrdU.
Structure Level Pattern Image Note
TS20: diencephalon Present Regionally restricted 5H Control Expressed in the thalamic eminence.

Specimen 5H -/-: embryonic day 12.5; Lhx2tm1Dra/Lhx2tm1Dra (more )
Note: Double labeled: red - Mki67; green - BrdU.
Structure Level Pattern Image Note
TS20: diencephalon Present Regionally restricted 5H -/- Expressed in the thalamic eminence. The quit fraction (BrdU+; Ki67- cells/total BrdU+ cells) was significantly greater in the mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory