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Gene Expression Data
Assay Details
Assay
Reference: J:210131 Roy A, et al., Lhx2 regulates the development of the forebrain hem system. Cereb Cortex. 2014 May;24(5):1361-72
Assay type: RNA in situ
MGI Accession ID: MGI:7511689
Gene symbol: Zic2
Gene name: zinc finger protein of the cerebellum 2
Probe: Zic2 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1J: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 1J Expressed broadly in the septum.
Specimen 1K: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cortical hem Present 1K
TS20: diencephalon Present Regionally restricted 1K Expressed in the thalamic eminence.
Specimen 1L: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cortical hem Present 1L
TS20: diencephalon Present Regionally restricted 1L Expressed in the thalamic eminence.
Specimen 1M: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cortical hem Present 1M
TS20: telencephalon Present Regionally restricted 1M Expressed in the septum.
TS20: diencephalon Present Regionally restricted 1M Expressed in the thalamic eminence.
Specimen 3E/F Control: embryonic day 12.5 (more )
Note: False-color overlays of adjacent sections: red - Zic2; green - Neurog2 (assay MGI:7511699).
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 3E Control , 3F Control Expressed in both components of the septum and also adjacent medial pallial regions.
TS20: pallium Present Regionally restricted 3F Control , 3E Control Expressed in the medial pallial regions adjacent to the septum.
Specimen 3E/F -/-: embryonic day 12.5; Lhx2tm1Dra/Lhx2tm1Dra (more )
Note: False-color overlays of adjacent sections: red - Zic2; green - Neurog2 (assay MGI:7511699).
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 3E -/- , 3F -/- Expression extended into the territory from which Neurog2 had receded. Neurog2 and Zic2 expressions overlapped in the cortical hem.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory