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Gene Expression Data
Assay Details
Assay
Reference: J:103991 Ijiri K, et al., A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation. J Biol Chem. 2005 Nov 18;280(46):38544-55
Assay type: RNA in situ
MGI Accession ID: MGI:7506320
Gene symbol: Mmp13
Gene name: matrix metallopeptidase 13
Probe: Mmp13 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3H: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: tibia hypertrophic chondrocyte Present Regionally restricted 3H Expression is in late stage hypertrophic chondrocytes.

Specimen 3K: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: tibia hypertrophic chondrocyte Present Regionally restricted 3K Expression is in late stage hypertrophic chondrocytes.

Specimen 4C: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: tibia hypertrophic chondrocyte Present Regionally restricted 4C Expression is in hypertrophic chondrocytes.

Specimen 4F: embryonic day 15.5; Gadd45btm1Flv/Gadd45btm1Flv (more )
Structure Cell Type Level Pattern Image Note
TS23: tibia hypertrophic chondrocyte Weak Regionally restricted 4F In this mutant the number and distribution of expressing hypertrophic chondrocytes was reduced compared to wild-type.

Specimen 4G: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: tibia hypertrophic chondrocyte Present Regionally restricted 4G Expression is in hypertrophic chondrocytes.

Specimen 4H: embryonic day 15.5; Gadd45btm1Flv/Gadd45btm1Flv (more )
Structure Cell Type Level Pattern Image Note
TS23: tibia hypertrophic chondrocyte Weak Regionally restricted 4H In this mutant the number and distribution of expressing hypertrophic chondrocytes was reduced compared to wild-type.

Specimen 5E WT: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: tibia hypertrophic chondrocyte Present Regionally restricted 5E WT Mmp13 Expression is in hypertrophic chondrocytes.

Specimen 5E Gadd45b-/-: embryonic day 16.5; Gadd45btm1Flv/Gadd45btm1Flv (more )
Structure Cell Type Level Pattern Image Note
TS24: tibia hypertrophic chondrocyte Weak Regionally restricted 5E Gadd45b-/- Mmp13 In this mutant the number and distribution of expressing hypertrophic chondrocytes was reduced compared to wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory