Arx RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:141473 Biressi S, et al., The homeobox gene Arx is a novel positive regulator of embryonic myogenesis. Cell Death Differ. 2008 Jan;15(1):94-104
Assay type:	RNA in situ
MGI Accession ID:	MGI:7495874
Gene symbol:	Arx
Gene name:	aristaless related homeobox

Probe:	Arx probe
Probe preparation:	Antisense labelled with digoxigenin RNA

Results

Specimen E9.5 not shown: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: myotome	Absent			No expression in newly formed myotomes.

Specimen 2a: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: myotome	Present	Graded	2a	Expression in cranial-caudal gradient, both in epaxial (dorsal) and hypaxial (ventral) domains of myotomes.
TS17: telencephalon	Present		2a
TS17: 1st branchial arch	Present		2a

Specimen E10.5 not shown: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Present
TS17: pancreas primordium	Present

Specimen 2b: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: limb	Present		2b	Expression in forming muscle masses.

Specimen 2d: embryonic day 13.0 (more

)

Structure	Level	Pattern	Image	Note
TS21: eye skeletal muscle	Present		2d
TS21: intercostal muscle	Present		2d
TS21: craniocervical region muscle	Present	Regionally restricted	2d	Expression in branchial muscle.

Specimen 3a: embryonic day 10.5 (more

)

Structure	Level	Image
TS17: myotome	Present	3a
TS17: neural tube	Present	3a
TS17: pancreas primordium	Present	3a
TS17: telencephalon	Present	3a

Specimen 3b: embryonic day 10.5; Myf5^tm1Pas/Myf5^tm1Pas, Myod1^tm1Jae/Myod1^tm1Jae (more

)

Structure	Level	Image	Note
TS17: myotome	Absent	3b	Expression undetected in somitic compartment.
TS17: neural tube	Present	3b	Expression maintained in pancreas and central nervous system.
TS17: pancreas primordium	Present	3b	Expression maintained in pancreas and central nervous system.
TS17: telencephalon	Present	3b	Expression maintained in pancreas and central nervous system.

Specimen 3c,c': embryonic day 11.5 (more

)

Structure	Level	Image
TS19: myotome	Present	3c , 3c'
TS19: neural tube	Present	3c , 3c'
TS19: pancreas primordium	Present	3c , 3c'
TS19: telencephalon	Present	3c , 3c'

Specimen 3d,d': embryonic day 11.5; Myf5^tm1Pas/Myf5^tm1Pas, Myod1^tm1Jae/Myod1^tm1Jae (more

)

Structure	Level	Image	Note
TS19: myotome	Absent	3d , 3d'	Expression undetected in somitic compartment.
TS19: neural tube	Present	3d , 3d'	Expression maintained in pancreas and central nervous system
TS19: pancreas primordium	Present	3d , 3d'	Expression maintained in pancreas and central nervous system
TS19: telencephalon	Present	3d , 3d'	Expression maintained in pancreas and central nervous system

Specimen 7b: embryonic day 12.0 (more

)

Structure	Level	Pattern	Image	Note
TS20: myotome	Present		7b

Specimen 7c: embryonic day 12.0; Myod1^tm1Jae/Myod1^tm1Jae (more

)

Structure	Level	Pattern	Image	Note
TS20: myotome	Weak		7c	Expression reduced compared to wild type.

Specimen 7d: embryonic day 12.0; Myf5^tm2Tajb/Myf5^tm2Tajb (more

)

Structure	Level	Pattern	Image	Note
TS20: myotome	Weak		7d	Expression reduced compared to wild type.

Specimen 7e: embryonic day 12.0; Myf5^tm2Tajb/Myf5^tm2Tajb, Myod1^tm1Jae/Myod1^tm1Jae (more

)

Structure	Level	Pattern	Image	Note
TS20: myotome	Weak		7e	Expression reduced compared to wild type.

Specimen 7f: embryonic day 12.0; Myf5^tm1Pas/Myf5^tm1Pas (more

)

Structure	Level	Pattern	Image	Note
TS20: myotome	Weak		7f	Expression reduced compared to wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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